Detalhe da pesquisa
1.
Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.
Proc Natl Acad Sci U S A
; 119(46): e2208804119, 2022 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36343253
2.
SAR study of 1,2-benzisothiazole dioxide compounds that agonize HIF-2 stabilization and EPO production.
Bioorg Med Chem
; 77: 117041, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36521398
3.
Structural basis for the allosteric inhibition of hypoxia-inducible factor (HIF)-2 by belzutifan.
Mol Pharmacol
; 2022 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36167425
4.
Bidirectional modulation of HIF-2 activity through chemical ligands.
Nat Chem Biol
; 15(4): 367-376, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804532
5.
Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes.
Int J Antimicrob Agents
; 63(5): 107160, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38537721
6.
Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-XL by engaging a single-residue discrepancy.
Nat Commun
; 15(1): 1476, 2024 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38368459
7.
Docking-guided rational engineering of a macrolide glycosyltransferase glycodiversifies epothilone B.
Commun Biol
; 5(1): 100, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35087210
8.
Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.
Nat Commun
; 13(1): 2529, 2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534502
9.
Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis.
Nat Commun
; 12(1): 296, 2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33436600
10.
Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution.
Biochim Biophys Acta Gen Subj
; 1863(7): 1167-1176, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31004719
11.
Single-Stranded DNA-Binding Protein and Exogenous RecBCD Inhibitors Enhance Phage-Derived Homologous Recombination in Pseudomonas.
iScience
; 14: 1-14, 2019 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30921732