Detalhe da pesquisa
1.
TNAP and P2X7R: New Plasma Biomarkers for Alzheimer's Disease.
Int J Mol Sci
; 24(13)2023 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446074
2.
TNAP upregulation is a critical factor in Tauopathies and its blockade ameliorates neurotoxicity and increases life-expectancy.
Neurobiol Dis
; 165: 105632, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35065251
3.
The regulation of proteostasis in glial cells by nucleotide receptors is key in acute neuroinflammation.
FASEB J
; 32(6): 3020-3032, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29401585
4.
Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology.
J Neurosci
; 37(30): 7063-7072, 2017 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28747389
5.
Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation.
Hum Mol Genet
; 25(19): 4143-4156, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466191
6.
The Neurotoxic Role of Extracellular Tau Protein.
Int J Mol Sci
; 19(4)2018 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29584657
7.
Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy.
J Neurosci
; 36(22): 5920-32, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27251615
8.
Regulation of proteasome activity by P2Y2 receptor underlies the neuroprotective effects of extracellular nucleotides.
Biochim Biophys Acta Mol Basis Dis
; 1863(1): 43-51, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27768902
9.
TNAP stimulates vascular smooth muscle cell trans-differentiation into chondrocytes through calcium deposition and BMP-2 activation: Possible implication in atherosclerotic plaque stability.
Biochim Biophys Acta Mol Basis Dis
; 1863(3): 643-653, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27932058
10.
TNAP Plays a Key Role in Neural Differentiation as well as in Neurodegenerative Disorders.
Subcell Biochem
; 76: 375-85, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26219721
11.
Diadenosine tetraphosphate contributes to carbachol-induced tear secretion.
Purinergic Signal
; 11(1): 87-93, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25398705
12.
α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease.
Hum Mol Genet
; 21(3): 495-510, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22045698
13.
Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation.
J Cell Sci
; 125(Pt 1): 176-88, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22250198
14.
The specificity protein factor Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system.
J Biol Chem
; 287(53): 44628-44, 2012 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23139414
15.
Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice.
FASEB J
; 26(4): 1616-28, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22198387
16.
Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079.
Epilepsia
; 54(9): 1551-61, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23808395
17.
P2X7 receptor inhibition ameliorates ubiquitin-proteasome system dysfunction associated with Alzheimer's disease.
Alzheimers Res Ther
; 15(1): 105, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37287063
18.
Looking for novel functions of tau.
Biochem Soc Trans
; 40(4): 653-5, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22817710
19.
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.
Brain
; 134(Pt 1): 119-36, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20929960
20.
Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment.
Proc Natl Acad Sci U S A
; 106(33): 13986-91, 2009 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19666572