Pesquisa | Biblioteca Virtual em Saúde

1.

Preclinical Evaluation of IMGC936, a Next-Generation Maytansinoid-based Antibody-drug Conjugate Targeting ADAM9-expressing Tumors.

Scribner, Juniper A; Hicks, Stuart W; Sinkevicius, Kerstin W; Yoder, Nicholas C; Diedrich, Gundo; Brown, Jennifer G; Lucas, Jacquelynn; Fuller, Megan E; Son, Thomas; Dastur, Anahita; Hooley, Jeff; Espelin, Christopher; Themeles, Marian; Chen, Francine Z; Li, Ying; Chiechi, Michael; Lee, Jenny; Barat, Bhaswati; Widjaja, Lusiana; Gorlatov, Sergey; Tamura, James; Ciccarone, Valentina; Ab, Olga; McEachem, Kerry A; Koenig, Scott; Westin, Eric H; Moore, Paul A; Chittenden, Thomas; Gregory, Richard J; Bonvini, Ezio; Loo, Deryk.

Mol Cancer Ther ; 21(7): 1047-1059, 2022 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-35511740

2.

Multispecific, Multivalent Antibody-Based Molecules Engineered on the DART® and TRIDENT^TM Platforms.

Huang, Ling; Shah, Kalpana; Barat, Bhaswati; Lam, Chia-Ying K; Gorlatov, Sergey; Ciccarone, Valentina; Tamura, James; Moore, Paul A; Diedrich, Gundo.

Curr Protoc Immunol ; 129(1): e95, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32294319

3.

Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules.

Pollara, Justin; Edwards, R Whitney; Jha, Shalini; Lam, Chia-Ying Kao; Liu, Liqin; Diedrich, Gundo; Nordstrom, Jeffrey L; Huffman, Tori; Pickeral, Joy A; Denny, Thomas N; Permar, Sallie R; Ferrari, Guido.

Front Immunol ; 11: 713, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32373131

4.

Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule.

Berezhnoy, Alexey; Sumrow, Bradley J; Stahl, Kurt; Shah, Kalpana; Liu, Daorong; Li, Jonathan; Hao, Su-Shin; De Costa, Anushka; Kaul, Sanjeev; Bendell, Johanna; Cote, Gregory M; Luke, Jason J; Sanborn, Rachel E; Sharma, Manish R; Chen, Francine; Li, Hua; Diedrich, Gundo; Bonvini, Ezio; Moore, Paul A.

Cell Rep Med ; 1(9): 100163, 2020 12 22.

Artigo em Inglês | MEDLINE | ID: mdl-33377134

5.

Biochemical characterization of genetic mutations of GPR56 in patients with bilateral frontoparietal polymicrogyria (BFPP).

Ke, Ning; Ma, Hongwen; Diedrich, Gundo; Chionis, John; Liu, Guohong; Yu, De-Hua; Wong-Staal, Flossie; Li, Qi-Xiang.

Biochem Biophys Res Commun ; 366(2): 314-20, 2008 Feb 08.

Artigo em Inglês | MEDLINE | ID: mdl-18042463

6.

How does hepatitis C virus enter cells?

Diedrich, Gundo.

FEBS J ; 273(17): 3871-85, 2006 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-16934030

7.

Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action.

Geoghegan, James C; Diedrich, Gundo; Lu, Xiaojun; Rosenthal, Kim; Sachsenmeier, Kris F; Wu, Herren; Dall'Acqua, William F; Damschroder, Melissa M.

MAbs ; 8(3): 454-67, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-26854859

8.

Targeting CD73 in the tumor microenvironment with MEDI9447.

Hay, Carl M; Sult, Erin; Huang, Qihui; Mulgrew, Kathy; Fuhrmann, Stacy R; McGlinchey, Kelly A; Hammond, Scott A; Rothstein, Raymond; Rios-Doria, Jonathan; Poon, Edmund; Holoweckyj, Nick; Durham, Nicholas M; Leow, Ching Ching; Diedrich, Gundo; Damschroder, Melissa; Herbst, Ronald; Hollingsworth, Robert E; Sachsenmeier, Kris F.

Oncoimmunology ; 5(8): e1208875, 2016 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-27622077

9.

Epitope binning of murine monoclonal antibodies by a multiplexed pairing assay.

Miller, Paul L; Wolfert, Robert L; Diedrich, Gundo.

J Immunol Methods ; 365(1-2): 118-25, 2011 Feb 28.

Artigo em Inglês | MEDLINE | ID: mdl-21223970

10.

Quantitation of p95HER2 in paraffin sections by using a p95-specific antibody and correlation with outcome in a cohort of trastuzumab-treated breast cancer patients.

Sperinde, Jeff; Jin, Xueguang; Banerjee, Jayee; Penuel, Elicia; Saha, Anasuya; Diedrich, Gundo; Huang, Weidong; Leitzel, Kim; Weidler, Jodi; Ali, Suhail M; Fuchs, Eva-Maria; Singer, Christian F; Köstler, Wolfgang J; Bates, Michael; Parry, Gordon; Winslow, John; Lipton, Allan.

Clin Cancer Res ; 16(16): 4226-35, 2010 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-20664024

11.

A characterization of the lumenal region of human tapasin reveals the presence of two structural domains.

Chen, Mingnan; Stafford, Walter F; Diedrich, Gundo; Khan, Amir; Bouvier, Marlene.

Biochemistry ; 41(49): 14539-45, 2002 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-12463753

12.

Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57.

Radcliffe, Catherine M; Diedrich, Gundo; Harvey, David J; Dwek, Raymond A; Cresswell, Peter; Rudd, Pauline M.

J Biol Chem ; 277(48): 46415-23, 2002 Nov 29.

Artigo em Inglês | MEDLINE | ID: mdl-12235131

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