Detalhe da pesquisa
1.
Chemotactic Interactions Drive Migration of Membraneless Active Droplets.
J Am Chem Soc
; 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38620052
2.
Biochemical and cellular effects of a novel missense mutation of the AGXT gene associated with Primary Hyperoxaluria Type 1.
Biochem Biophys Res Commun
; 645: 118-123, 2023 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36682331
3.
Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase.
Proteins
; 90(2): 435-442, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34495558
4.
The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization.
Mol Genet Metab
; 131(1-2): 171-180, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32792227
5.
New variants of AADC deficiency expand the knowledge of enzymatic phenotypes.
Arch Biochem Biophys
; 682: 108263, 2020 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31953134
6.
Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat Chem Biol
; 14(6): 548-555, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29686356
7.
Publisher Correction: Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat Chem Biol
; 14(10): 988, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29760514
8.
Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1.
Biochem J
; 476(24): 3751-3768, 2019 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794008
9.
Pyridoxal 5'-Phosphate-Dependent Enzymes at the Crossroads of Host-Microbe Tryptophan Metabolism.
Int J Mol Sci
; 21(16)2020 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32823705
10.
Biochemical properties and oxalate-degrading activity of oxalate decarboxylase from bacillus subtilis at neutral pH.
IUBMB Life
; 71(7): 917-927, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30806021
11.
Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6.
J Inherit Metab Dis
; 41(2): 263-275, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29110180
12.
Folding Defects Leading to Primary Hyperoxaluria.
Handb Exp Pharmacol
; 245: 313-343, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29071511
13.
The novel R347g pathogenic mutation of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency.
Biochim Biophys Acta
; 1864(6): 676-682, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26994895
14.
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine.
Biochim Biophys Acta
; 1854(10 Pt A): 1280-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26149463
15.
A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications.
Hum Mol Genet
; 23(20): 5429-40, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24865461
16.
S250F variant associated with aromatic amino acid decarboxylase deficiency: molecular defects and intracellular rescue by pyridoxine.
Hum Mol Genet
; 22(8): 1615-24, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23321058
17.
Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches.
Front Mol Biosci
; 11: 1386598, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38721278
18.
Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study.
Sci Rep
; 13(1): 22692, 2023 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38123809
19.
Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1.
J Med Chem
; 65(14): 9718-9734, 2022 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35830169
20.
Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase.
Protein Sci
; 31(5): e4303, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35481644