Detalhe da pesquisa
1.
Development of tetravalent, bispecific CCR5 antibodies with antiviral activity against CCR5 monoclonal antibody-resistant HIV-1 strains.
Antimicrob Agents Chemother
; 55(5): 2369-78, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300827
2.
Synthesis, SAR and evaluation of [1,4']-bipiperidinyl-4-yl-imidazolidin-2-one derivatives as novel CCR5 antagonists.
Bioorg Med Chem Lett
; 20(11): 3219-22, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20457517
3.
Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists.
Bioorg Med Chem Lett
; 20(10): 3116-9, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20417098
4.
Spiropiperidine CCR5 antagonists.
Bioorg Med Chem Lett
; 19(18): 5401-6, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19674898
5.
Molecular interactions of CCR5 with major classes of small-molecule anti-HIV CCR5 antagonists.
Mol Pharmacol
; 73(3): 789-800, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18096812
6.
Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities.
Antiviral Res
; 74(2): 125-37, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17166600
7.
A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands.
Br J Pharmacol
; 171(14): 3364-75, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24628038
8.
The second extracellular loop of CCR5 contains the dominant epitopes for highly potent anti-human immunodeficiency virus monoclonal antibodies.
Antimicrob Agents Chemother
; 51(4): 1386-97, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17242138
9.
CCR5 small-molecule antagonists and monoclonal antibodies exert potent synergistic antiviral effects by cobinding to the receptor.
Mol Pharmacol
; 72(1): 18-28, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17392523
10.
Analyzing ligand and small molecule binding activity of solubilized GPCRs using biosensor technology.
Anal Biochem
; 355(1): 132-9, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16762304