Detalhe da pesquisa
1.
High-throughput in Vitro Data To Inform Prioritization of Ambient Water Monitoring and Testing for Endocrine Active Chemicals.
Environ Sci Technol
; 52(2): 783-793, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29214797
2.
Development and Validation of a Computational Model for Androgen Receptor Activity.
Chem Res Toxicol
; 30(4): 946-964, 2017 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933809
3.
Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses.
Environ Sci Technol
; 48(15): 8706-16, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24960280
4.
Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays.
Chem Res Toxicol
; 26(6): 878-95, 2013 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23611293
5.
Real-time growth kinetics measuring hormone mimicry for ToxCast chemicals in T-47D human ductal carcinoma cells.
Chem Res Toxicol
; 26(7): 1097-107, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23682706
6.
Predictive model of rat reproductive toxicity from ToxCast high throughput screening.
Biol Reprod
; 85(2): 327-39, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21565999
7.
Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment.
Chem Res Toxicol
; 24(4): 451-62, 2011 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21384849
8.
Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.
Chem Res Toxicol
; 23(3): 578-90, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20143881
9.
Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals.
J Toxicol Environ Health B Crit Rev
; 13(2-4): 329-46, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20574906
10.
Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity.
Environ Sci Technol
; 44(15): 5979-85, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20602530
11.
Toxicogenomic effects common to triazole antifungals and conserved between rats and humans.
Toxicol Appl Pharmacol
; 238(1): 80-9, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19409404
12.
Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout mice.
Birth Defects Res A Clin Mol Teratol
; 85(8): 732-40, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19639652
13.
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.
Nat Biotechnol
; 24(9): 1151-61, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16964229
14.
Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy.
Circulation
; 113(22): 2589-97, 2006 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16735677
15.
The ToxCast program for prioritizing toxicity testing of environmental chemicals.
Toxicol Sci
; 95(1): 5-12, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16963515
16.
Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity.
Toxicol Sci
; 97(2): 595-613, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17383973
17.
Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.
Toxicol Sci
; 95(1): 227-39, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17018648
18.
Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice.
Mol Cell Biol
; 24(2): 899-911, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14701760
19.
Application of Adverse Outcome Pathways to U.S. EPA's Endocrine Disruptor Screening Program.
Environ Health Perspect
; 125(9): 096001, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934726
20.
Fluconazole-induced hepatic cytochrome P450 gene expression and enzymatic activities in rats and mice.
Toxicol Lett
; 164(1): 44-53, 2006 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16406388