Detalhe da pesquisa
1.
Design and optimization of selective azaindole amide M1 positive allosteric modulators.
Bioorg Med Chem Lett
; 26(2): 650-655, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631313
2.
Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation.
Front Pharmacol
; 11: 1005, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32733245
3.
α5 nAChR modulation of the prefrontal cortex makes attention resilient.
Brain Struct Funct
; 223(2): 1035-1047, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29299690
4.
Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization.
J Med Chem
; 61(24): 11384-11397, 2018 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30431269
5.
Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects.
ACS Chem Neurosci
; 8(1): 165-177, 2017 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27715007
6.
Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects.
J Med Chem
; 59(13): 6313-28, 2016 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27275946
7.
Pharmacological disruption of mouse social approach behavior: relevance to negative symptoms of schizophrenia.
Behav Brain Res
; 252: 405-14, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23806621