Detalhe da pesquisa
1.
Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design.
Bioorg Med Chem Lett
; 89: 129277, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37105490
2.
Atrial Fibrillation as a Predictor of Mortality in High Risk COVID-19 Patients: A Multicentre Study of 171 Patients.
Heart Lung Circ
; 30(8): 1151-1156, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33781697
3.
Regarding "The Clinical and Economic Burden of Norovirus Gastroenteritis in the United States".
J Infect Dis
; 224(4): 736-738, 2021 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33791801
4.
α-Aryl pyrrolidine sulfonamides as TRPA1 antagonists.
Bioorg Med Chem Lett
; 26(2): 495-498, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26706172
5.
Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors.
Bioorg Med Chem Lett
; 25(22): 5258-64, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26459208
6.
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.
ACS Med Chem Lett
; 15(1): 21-28, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229748
7.
Cis-amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase.
Bioorg Med Chem Lett
; 23(3): 897-901, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23265894
8.
Structure-based design of thienobenzoxepin inhibitors of PI3-kinase.
Bioorg Med Chem Lett
; 21(13): 4054-8, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21636270
9.
Recreational Nitrous Oxide-Induced Subacute Combined Degeneration of the Spinal Cord.
Cureus
; 13(11): e19377, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34909324
10.
Ignatzschineria spp. bacteremia from maggot infestation.
IDCases
; 25: e01151, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34136350
11.
Cytochalasin B Treatment and Osmotic Pressure Enhance the Production of Extracellular Vesicles (EVs) with Improved Drug Loading Capacity.
Nanomaterials (Basel)
; 12(1)2021 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35009953
12.
Amide-based inhibitors of p38alpha MAP kinase. Part 2: design, synthesis and SAR of potent N-pyrimidyl amides.
Bioorg Med Chem Lett
; 20(8): 2560-3, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20346659
13.
Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity.
ACS Med Chem Lett
; 11(3): 327-333, 2020 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32184965
14.
The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells.
Sci Signal
; 13(634)2020 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32487715
15.
Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.
J Med Chem
; 62(4): 2140-2153, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30715878
16.
Aryl-indolyl maleimides as inhibitors of CaMKIIdelta. Part 3: Importance of the indole orientation.
Bioorg Med Chem Lett
; 18(7): 2399-403, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18337095
17.
Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling.
J Med Chem
; 61(8): 3641-3659, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590749
18.
Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability.
J Med Chem
; 60(10): 4458-4473, 2017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28445037
19.
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.
Cancer Res
; 63(21): 7345-55, 2003 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14612533
20.
The Rational Design of Selective Benzoxazepin Inhibitors of the α-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326).
J Med Chem
; 59(3): 985-1002, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26741947