Detalhe da pesquisa
1.
Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins.
PLoS Pathog
; 18(1): e1010226, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007288
2.
Complement MASP-1 Modifies Endothelial Wound Healing.
Int J Mol Sci
; 25(7)2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38612857
3.
The Lectin Pathway of the Complement System-Activation, Regulation, Disease Connections and Interplay with Other (Proteolytic) Systems.
Int J Mol Sci
; 25(3)2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38338844
4.
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation.
J Biol Chem
; 298(6): 101985, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483450
5.
Proprotein Convertase Is the Highest-Level Activator of the Alternative Complement Pathway in the Blood.
J Immunol
; 206(9): 2198-2205, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33858964
6.
Cooperation of Complement MASP-1 with Other Proinflammatory Factors to Enhance the Activation of Endothelial Cells.
Int J Mol Sci
; 24(11)2023 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298134
7.
Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum.
PLoS Pathog
; 15(12): e1008232, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31860690
8.
Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation.
J Immunol
; 200(7): 2247-2252, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29475986
9.
The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond.
Immunol Rev
; 274(1): 98-111, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27782318
10.
Correction: Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation.
J Biol Chem
; 299(1): 102807, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36563463
11.
MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors.
J Immunol
; 196(2): 857-65, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673137
12.
Comment on "Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway".
J Immunol
; 203(12): 3091, 2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31818918
13.
Soluble components of the flagellar export apparatus, FliI, FliJ, and FliH, do not deliver flagellin, the major filament protein, from the cytosol to the export gate.
Biochim Biophys Acta
; 1843(11): 2414-23, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25068520
14.
Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2.
Proc Natl Acad Sci U S A
; 109(26): 10498-503, 2012 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22691502
15.
Structural basis for activation of the complement system by component C4 cleavage.
Proc Natl Acad Sci U S A
; 109(38): 15425-30, 2012 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22949645
16.
Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway.
J Biol Chem
; 288(13): 8922-34, 2013 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23386610
17.
Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 Are essential for lectin pathway activation and reveal structural plasticity of MASP-2.
J Biol Chem
; 287(24): 20290-300, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22511776
18.
Inhibition of the serine proteases of the complement system.
Adv Exp Med Biol
; 735: 23-40, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23402017
19.
Quantification of the zymogenicity and the substrate-induced activity enhancement of complement factor D.
Front Immunol
; 14: 1197023, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37283768
20.
Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels.
Front Immunol
; 14: 1226832, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37771595