Detalhe da pesquisa
1.
Photoswitchable molecular glue for RNA: reversible photocontrol of structure and function of the ribozyme.
Nucleic Acids Res
; 51(18): 9533-9541, 2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37615580
2.
Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit.
Nucleic Acids Res
; 50(9): 5369-5383, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35511080
3.
Unique Crosslinking Properties of Psoralen-Conjugated Oligonucleotides Developed by Novel Psoralen N-Hydroxysuccinimide Esters.
Chembiochem
; 24(15): e202200789, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36896628
4.
Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation.
Nucleic Acids Res
; 49(16): 9479-9495, 2021 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34358321
5.
Synthesis and Evaluation of Oligonucleotide-Containing 2'-O-{[(4,5',8-Trimethylpsoralen)-4'-ylmethoxy]ethylaminocarb-onyl}adenosine as Photo-crosslinkable Gene Targeting Tools.
Chem Pharm Bull (Tokyo)
; 70(10): 726-730, 2022 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35896347
6.
Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats.
Nucleic Acids Res
; 47(20): 10906-10913, 2019 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31566242
7.
Recognition of expanded GGGGCC hexanucleotide repeat by synthetic ligand through interhelical binding.
Biochem Biophys Res Commun
; 531(1): 56-61, 2020 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32278549
8.
The Dimeric Form of 1,3-Diaminoisoquinoline Derivative Rescued the Mis-splicing of Atp2a1 and Clcn1 Genes in Myotonic Dystrophy Typeâ 1 Mouse Model.
Chemistry
; 26(63): 14305-14309, 2020 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32449537
9.
Molecular Glue for RNA: Regulating RNA Structure and Function through Synthetic RNA Binding Molecules.
Chembiochem
; 20(23): 2903-2910, 2019 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31087756
10.
A Dimeric 2,9-Diamino-1,10-phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Typeâ 1 Cell and Mouse Models.
Chemistry
; 24(68): 18115-18122, 2018 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30302858
11.
Cyclic mismatch binding ligand CMBL4 binds to the 5'-T-3'/5'-GG-3' site by inducing the flipping out of thymine base.
Nucleic Acids Res
; 44(15): 7090-9, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466390
12.
Restoration of Ribozyme Tertiary Contact and Function by Using a Molecular Glue for RNA.
Angew Chem Int Ed Engl
; 57(2): 506-510, 2018 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29143424
13.
Design and Synthesis of Cyclic Mismatch-Binding Ligands (CMBLs) with Variable Linkers by Ring-Closing Metathesis and their Photophysical and DNA Repeat Binding Properties.
Chemistry
; 23(47): 11385-11396, 2017 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28653774
14.
A Ligand That Targets CUG Trinucleotide Repeats.
Chemistry
; 22(42): 14881-14889, 2016 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27573860
15.
Synthesis of 1H-pyrrolo[3,2-h]quinoline-8-amine derivatives that target CTG trinucleotide repeats.
Bioorg Med Chem Lett
; 26(15): 3761-4, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27287365
16.
2-Aminophenanthroline dimer stabilized the C-C mismatched duplex DNA.
Bioorg Med Chem
; 23(4): 753-8, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25596168
17.
Formation of a ligand-assisted complex of two RNA hairpin loops.
Chemistry
; 20(18): 5282-7, 2014 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24644006
18.
Modulation of binding properties of amphiphilic DNA containing multiple dodecyl phosphotriester linkages to lipid bilayer membrane.
Bioorg Med Chem Lett
; 24(15): 3578-81, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24909080
19.
Naphthyridine tetramer with a pre-organized structure for 1:1 binding to a CGG/CGG sequence.
Nucleic Acids Res
; 40(6): 2771-81, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22127864
20.
A synthetic riboswitch that operates using a rationally designed ligand-RNA pair.
Angew Chem Int Ed Engl
; 52(38): 9976-9, 2013 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24030897