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1.
Pediatr Exerc Sci ; 31(4): 401-407, 2019 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-30955442

RESUMO

PURPOSE: To assess glycemic control and safety of children and adolescents with type 1 diabetes participating in a 2-day football tournament. METHODS: In total, 189 children with type 1 diabetes from 11 diabetes care centers, in Poland, participated in a football tournament in 3 age categories: 7-9 (21.2%), 10-13 (42.9%), and 14-17 (36%) years. Participants were qualified and organized in 23 football teams, played 4 to 6 matches of 30 minutes, and were supervised by a medical team. Data on insulin dose and glycemia were downloaded from personal pumps, glucose meters, continuous glucose monitoring, and flash glucose monitoring systems. RESULTS: The median level of blood glucose before the matches was 6.78 (4.89-9.39) mmol/L, and after the matches, it was 7.39 (5.5-9.87) mmol/L (P = .001). There were no episodes of severe hypoglycemia or ketoacidosis. The number of episodes of low glucose value (blood glucose ≤3.9 mmol/L) was higher during the tournament versus 30 days before: 1.2 (0-1.5) versus 0.7 (0.3-1.1) event/person/day, P < .001. Lactate levels increased during the matches (2.2 [1.6-4.0] mmol/L to 4.4 [2.6-8.5] mmol/L after the matches, P < .001). CONCLUSIONS: Large football tournaments can be organized safely for children with type 1 diabetes. For the majority of children, moderate mixed aerobic-anaerobic effort did not adversely affect glycemic results and metabolic safety.


Assuntos
Glicemia/metabolismo , Diabetes Mellitus Tipo 1/fisiopatologia , Segurança , Futebol/fisiologia , Adolescente , Criança , Diabetes Mellitus Tipo 1/sangue , Diabetes Mellitus Tipo 1/tratamento farmacológico , Feminino , Humanos , Hipoglicemia/sangue , Hipoglicemia/diagnóstico , Hipoglicemia/etiologia , Hipoglicemiantes/uso terapêutico , Insulina/uso terapêutico , Ácido Láctico/sangue , Masculino
2.
Biology (Basel) ; 12(4)2023 Apr 12.
Artigo em Inglês | MEDLINE | ID: mdl-37106789

RESUMO

BACKGROUND: Menopause is a time when women experience a number of physiological and anatomical changes resulting from a decline in ovarian function. It can be concluded that cardiovascular disease increases in perimenopausal and postmenopausal women, irrespective of age-related changes. Engaging in the amount of moderate physical activity recommended by the World Health Organization helps reduce the risk of death and adverse health events. The aim of the present study was to assess the effect of a 6-month aqua aerobics programme on cardiometabolic (anthropometric and biochemical) parameters in perimenopausal women. METHODS: In this study, 30 women (control group-16, study group-14) participated in the 6-month aqua aerobics training programme. The mean age of women was 47.67 ± 6.79 year and BMI 26.33 ± 3.64 kg/m2. At the beginning and at the end of the study, anthropometric and blood samples analysis were performed. In the blood, lipid profile, morphotic elements were determined. Body composition, waist-hip ratio (WHR), visceral adiposity index (VAI), blood pressure (BP) were measured. RESULTS: The aqua aerobics programme resulted in a significant decrease in the WHR (p < 0.05; ES: 2.143), diastolic blood pressure (DBP) (p < 0.05; ES: 1.005), and platelet-to-lymphocyte ratio (PRL) (p < 0.05; ES: 0.460) and an increase in haemoglobin (HGB) concentration (p < 0.05; ES: 0.643). CONCLUSIONS: The type of physical activity described in the present study is a great way for perimenopausal women to take care of their overall well-being. The reduction in selected cardiometabolic parameters is important from the point of view of the protection of women's health.

3.
Biology (Basel) ; 12(2)2023 Jan 23.
Artigo em Inglês | MEDLINE | ID: mdl-36829458

RESUMO

BACKGROUND: Age-related reduction in exercise capacity is manifested by a rapid development of fatigue. Research confirmed the adverse prognostic value of red blood cell distribution width (RDW-CV), an independent factor in heart failure, coronary heart disease and myocardial infarction. Physical exercise improves and helps to maintain cardiorespiratory fitness. The aim of our study was to examine the impact of 8 weeks' Nordic walking training with classic poles (NW) and NW training with poles with an integrated resistance shock absorber (NW with RSA) on RDW-CV levels and to assess correlations between RDW-CV levels and cardiorespiratory performance in postmenopausal women. METHODS: In this study, 32 postmenopausal women (NW-16, NW with RSA-16) participated in eight weeks of walking training. The mean age of women was 66.56 ± 4.23 year. and BMI 26.99 ± 3.86 kg/m2. At the beginning and at the end of the study, spirometry and exercise tests were performed. Haematological parameters were determined in the venous blood. RESULTS: Statistical analysis of differences in post-training changes in the parameters between the groups studied showed a significant difference in change in body weight (∆body weight) (p < 0.05; ES: 0.778), BMI (∆BMI) (p < 0.05; ES: 0.778), waist circumference (∆WC) (p < 0.05; ES: 1.225) and (∆RDW-SD) (p < 0.05; ES: 1.215). There were no changes in electrocardiographic and spirometric parameters. CONCLUSIONS: Based on the findings from the present study, it can be assumed that endurance and resistance exercise can significantly reduce disease severity and mortality. A clinical analysis of RDW levels, together with other cardiological and biochemical parameters, can provide practical prognostic information relating to cardiovascular disease, mortality risk and treatment outcomes.

4.
Nutrients ; 15(1)2023 Jan 03.
Artigo em Inglês | MEDLINE | ID: mdl-36615898

RESUMO

Background: The aim of this study was to determine the effect of using an oxygen-enriched breathing mixture during controlled physical training on blood oxidative stress parameters and total phenolics (TP) concentrations in obese adult women. Methods: A prospective randomized controlled trial study included 60 women aged 19−68 with BMIs greater than 30 kg/m2. Patients were randomly assigned to the study group (n = 30), which received additional intervention in supplementing the breathing mixture with oxygen at the flow of 6 L/min during training sessions, and the control group (n = 30). At the beginning and at the end of the study, anthropometric assessments (height and weight and BMI) and blood tests (CRP, FRAP, TBARS, TP, BAC, and La) were performed. For each patient, an individual endurance training plan was established on a cycloergometer, including 12 training units, based on a cardiopulmonary exercise test (CPET). Results: A decrease in blood TBARS concentration was observed in each study group. For the control group, the change was more remarkable, and the difference between the groups was significant at (p < 0.05; ES: 0.583). Training with the oxygen breathing mixture increased blood concentrations of TP, while a decrease in TP in blood was observed in the group without oxygen supplementation during physical training. The difference in the responses between the groups was significant at (p < 0.05; ES: 0.657) Conclusions: Increasing the concentration of oxygen in the respiratory mixture under conditions of increased exercise was shown to be safe because it did not exacerbate oxidative stress in the obese group.


Assuntos
Obesidade , Estresse Oxidativo , Humanos , Adulto , Feminino , Substâncias Reativas com Ácido Tiobarbitúrico , Estudos Prospectivos , Obesidade/terapia , Oxigênio/farmacologia
5.
Exp Gerontol ; 174: 112116, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36739795

RESUMO

The aim of this study was to determine the effectiveness of a six-week time-restricted eating (TRE) intervention in reducing body weight, fat loss, and visceral fat in overweight, older adult men and women (age range = 65-74 years). Another objective was to determine the feasibility of widespread use of TRE in older women and men. The study randomly assigned 116 healthy, non-smoking participants to one of two conditions: TRE or educational control participants. Participants in the TRE group were instructed to not consume calorie containing beverages or food for 16 h per day, from 8:00 pm to 12:00 pm. Participants in the control group were instructed to follow a meal plan based on their previous habits. The changes in body weight and body composition were determined using a SECA mBCA 515 analyzer. The six-week TRE intervention resulted in a significant decrease in body weight in both men and women (-1.8 kg and-1.3 kg, respectively; p = 0.03). In men, a significant decrease in visceral fat mass (-0.54 l; p ≤ 0.001) and waist circumference (-2.9 cm; p ≤ 0.015) was observed. No significant changes in either visceral fat or waist circumference were observed in women. Additionally, no change in skeletal muscle mass was observed in either the control or TRE group. More than 99 % of female and 98 % of male participants were able to adhere to the prescribed time-restricted eating (16/8) plan, suggesting that this dietary approach could have beneficial effects on the body composition of overweight older men and may also reduce body weight in overweight, older women.


Assuntos
Obesidade , Sobrepeso , Idoso , Feminino , Humanos , Masculino , Composição Corporal/fisiologia , Peso Corporal/fisiologia , Gordura Intra-Abdominal , Redução de Peso/fisiologia
6.
J Clin Med ; 11(12)2022 Jun 20.
Artigo em Inglês | MEDLINE | ID: mdl-35743624

RESUMO

Research in modern neurorehabilitation focusses on cognitive and motor recovery programmes tailored to each stroke patient, with particular emphasis on physiological parameters. The objectives of this review were to determine whether a single bout of endurance activity or long-term endurance activity regulates exercise-dependent serum brain-derived neurotrophic factor (BDNF) levels and to evaluate the methodological quality of the studies. To assess the effectiveness of endurance exercise among patients in the chronic post-stroke phase, a systematic review was performed, including searching EBSCOhost, PEDro, PubMed, and Scopus for articles published up to the end of October 2021. The PRISMA 2020 outline was used, and this review was registered on PROSPERO. Of the 180 papers identified, seven intervention studies (comprising 200 patients) met the inclusion criteria. The methodological quality of these studies was evaluated by using the Physiotherapy Evidence Database (PEDro) criteria. The effect of exercise was evaluated in four studies with a single bout of endurance activity, two studies with long-term endurance activity, and one study with a single bout of endurance activity as well as long-term endurance activity. The results of our systematic review provide evidence that endurance exercise might augment the peripheral BDNF concentration in post-stroke individuals.

7.
Nutrients ; 14(9)2022 May 06.
Artigo em Inglês | MEDLINE | ID: mdl-35565914

RESUMO

Patients with chronic obstructive pulmonary disease (COPD) suffer from exercise intolerance, the sensation of dyspnea, and fatigue, which are the main reasons for limiting their physical activity. In addition to changes in the respiratory and circulatory systems in patients with COPD, peripheral muscle dysfunction, with numerous metabolic dysfunctions, is observed. One of the symptoms of the described anomalies, among others, is an antioxidative and prooxidative imbalance. The aim of the study was to demonstrate the impact of endurance training, carried out in the extended pulmonary rehabilitation program in COPD patients, on the imbalance between prooxidants and antioxidants in their bodies. Methods: The tests were carried out on a group of patients (n = 32) with COPD; 20 randomly selected people underwent a modified rehabilitation program during their rehabilitation stay, and the obtained results were compared with the results of 12 patients (control group) who were treated without endurance training. At the beginning and at the end of the study, spirometry and cardiopulmonary exercise tests (CPET) were performed. Oxidative stress (allantoin (All) and substances which react with thiobarbituric acid) and antioxidant (ferric reducing ability of plasma and total phenolics) parameters' concentrations were determined in the venous blood. Results: In the study group, greater post-training increases of VO2max (p = 0.0702) and FEV1/FVC (p < 0.05; ES: 0.436) were reported. The applied CPET at each time caused an increase in the All concentration (p < 0.05) in the study and control groups. Conclusions: Endurance training applied as a part of the rehabilitation process did not cause the additional aggravation of oxidative stress and blood total phenolics concentration.


Assuntos
Doença Pulmonar Obstrutiva Crônica , Antioxidantes/metabolismo , Exercício Físico , Terapia por Exercício/métodos , Tolerância ao Exercício , Humanos , Estresse Oxidativo
8.
Adv Clin Exp Med ; 31(9): 953-963, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35543201

RESUMO

BACKGROUND: Physical activity undertaken in the treatment process additionally increases the oxygen demand of the working muscles. It seems interesting to see whether a delivery of an enriched respiratory mixture can have an impact on lower acidification of working muscles and oxygenation of tissues. OBJECTIVES: To assess tissue saturation and the level of acidification at rest and during exercise while breathing atmospheric air or an oxygen-enriched mixture. MATERIAL AND METHODS: Tissue saturation and lactate concentration at rest and during exercise were assessed in 18 females with an average body mass index (BMI) of 42 kg/m2. The study regimen was as follows: day 1 - cardiopulmonary exercise testing (CPET) - determination of the threshold load; day 2 - 20 min of physical effort on a cycloergometer (threshold load, breathing atmospheric air); day 3 - 20 min of physical effort on a cycloergometer (threshold load, breathing mixture enriched with oxygen). Saturation measurements were performed in 3 places on the patient's body by measuring absorbance via near-infrared spectroscopy (NIRS). RESULTS: A significant decrease in heart rate (HR) at rest was found when using the oxygen-enriched air mixture (Z = 2.1339, p = 0.0328 (effect size (ES) = 0.478)). During the exercise, a significant decrease in saturation was shown only for the midpoint of the quadriceps muscles (Z = 2.1572, p = 0.309 (ES = 0.600)). Medium effect sizes were shown by the difference in resting and exercising lactate concentration change between the experimental models studied (Z = 2.5041, p = 0.0122 (ES = 0.707)). In the experimental models studied, different medium effect sizes were demonstrated in the resting and exercising lactate concentration change. CONCLUSIONS: Oxygen-enriched air mixture contributes to reducing hypoxia in working muscles of obese people. Oxygen supplementation can result in higher physical fitness levels. The implementation of oxygen-enriched air mixture is a promising therapeutic strategy for obese patients who exhibit high lactate concentrations after exercise.


Assuntos
Consumo de Oxigênio , Oxigênio , Exercício Físico/fisiologia , Feminino , Humanos , Ácido Láctico , Obesidade/terapia , Consumo de Oxigênio/fisiologia
9.
Artigo em Inglês | MEDLINE | ID: mdl-35206416

RESUMO

The aim of the study was the evaluation of the hormonal response of wheelchair rugby participants under the half-year training cycle. The study sample included 11 members of the Polish national wheelchair rugby team with spinal cord injury at the cervical level, ranging in age from 21 to 41 years, body weight (72.2 ± 11.53 kg), and body height (182.3 ± 6.11 cm). The disabled individuals with spinal cord injury subjected to the study constitute a homogeneous group in terms of age, body height, weight, and injury level. The study was carried out at the beginning and at the end of a 6-month training period. In the first and second examination, measurements of the peak oxygen uptake (peakVO2) and blood biochemical analysis were performed (Lactate dehydrogenase (LDH) activity and concentration of creatinine (Cr), total testosterone (TT), free testosterone (FT), and cortisol (C)). A significant change was observed in the concentration of C in the Wheelchair Rugby players' blood between two research periods (p < 0.05 (ES:0.76)) and a correlation between the post-training change in FT/C concentration and the change in Cr concentration (r = -0.6014, p < 0.05). The 6-month training period did not result in overloads within the group of players. However, due to the significant loss of the capacity of the spinal cord injury (SCI) and the possibility of a life-threatening trend, the anabolic/catabolic status of the players should be monitored using blood biochemical indices.


Assuntos
Futebol Americano , Traumatismos da Medula Espinal , Cadeiras de Rodas , Adulto , Futebol Americano/lesões , Humanos , Aptidão Física/fisiologia , Rugby , Adulto Jovem
10.
Front Psychiatry ; 13: 777394, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35546921

RESUMO

Background: Cognitive deficits occur in most patients with affective disorders. The role of neurotrophic factors (e.g., BDNF) as modulators of brain plasticity affecting neurocognitive abilities has been emphasized. Neurotrophin concentrations may change under the influence of various interventions, including physical activity. Selected studies have shown that cognitive function may also be affected by exercise. Aim: The aim of the study was to determine whether physical activity changes the concentration of neurotrophins and their receptors in patients with an episode of depression. It was also examined how one session of aerobic exercise affects cognitive control. Methods: The study included 41 participants. The subjects were asked to exercise on a cycloergometer for 40 min with individually selected exercise loads (70% VO2max). Before and shortly after the exercise blood samples were acquired to perform blood assays (proBDNF, BDNF, TrkB, NGFR). The participants also performed a Stroop test twice-before the exercise and 10 min after its cessation. Results: The single bout of physical exercise did not cause any significant changes in the concentration of neurotrophic factors. The SCWT results: both the mean reading time (29.3 s vs. 47.8 s) and the color naming time (36.7 s vs. 50.7 s) increased. The patients made more mistakes after physical exercise, both in part A (0.2 vs. 1.5) and B (0.6 vs. 1.5). The so-called interference effect decreased-the difference between naming and reading times was smaller after exercise (6.2 s vs. 2.4 s). No significant correlations were found between the concentrations of the studied neurotrophic factors and the Stroop test results. Conclusions: The results did not confirm changes in neurotrophin concentration under the influence of a single session of physical activity. The shortening of the interference time after exercise may be caused by practice effects. A significant limitation of the study is the use of the Stroop test twice in short intervals.

11.
Aging Dis ; 13(1): 129-143, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35111366

RESUMO

Aging is a complex, multietiological process and a major risk factor for most non-genetic, chronic diseases including geriatric syndromes that negatively affect healthspan and longevity. In the scenario of "healthy or good aging", especially during the COVID-19 era, the proper implementation of exercise as "adjuvant" or "polypill" to improve disease-related symptoms and comorbidities in the general population is a top priority. However, there is still a gap concerning studies analyzing influence of exercise training to immune system in older people. Therefore, the aim of this review is to provide a brief summary of well-established findings in exercise immunology and immunogerontology, but with a focus on the main exercise-induced mechanisms associated with aging of the immune system (immunosenescence). The scientific data strongly supports the notion that regular exercise as a low-cost and non-pharmacological treatment approach, when adjusted on an individual basis in elderly, induce multiple rejuvenating mechanisms: (1) affects the telomere-length dynamics (a "telo-protective" effect), (2) promote short- and long-term anti-inflammatory effects (via e.g., triggering the anti-inflammatory phenotype), 3) stimulates the adaptive immune system (e.g., helps to offset diminished adaptive responses) and in parallel inhibits the accelerated immunosenescence process, (4) increases post-vaccination immune responses, and (5) possibly extends both healthspan and lifespan.

12.
Sci Rep ; 12(1): 9816, 2022 06 14.
Artigo em Inglês | MEDLINE | ID: mdl-35701451

RESUMO

The main aim of the study was to determine the effectiveness of time-restricted eating (TRE) in reducing body fat and lowering body mass index in early elderly men with overweight (65-74 years). An additional goal was to determine the feasibility of applying TRE for extensive use in elderly men. This study included a group of 46 healthy men (EXP = 23 persons, CON = 23 persons). The six-week intervention in the experimental group involved complete abstinence from food intake for 16 h per day, from 08:00 to 12:00 p.m. After the intervention, the body weight decreased in the EXP group (- 1.92 kg) with a 95% CI (1.14-2.70) compared to the CON group. There was also a decrease in the Visceral fat mass (- 0.64 l) with 95% CI (0.46-0.82) and in the waist circumference (- 3.11 cm) with 95% CI (1.89-4.33) in the EXP group compared to the CON group. The skeletal muscle mass did not change significantly. There was no significant change in the control group, either. The application of TRE in early elderly overweight men resulted in positive changes in body composition and visceral fat. All participants succeed in the prescribed diet plan, which shows that TRE is easy to maintain for early elderly overweight men and may become an essential obesity treatment tool in these age groups.


Assuntos
Obesidade , Sobrepeso , Idoso , Composição Corporal/fisiologia , Índice de Massa Corporal , Humanos , Masculino , Sobrepeso/terapia , Circunferência da Cintura
13.
Artigo em Inglês | MEDLINE | ID: mdl-34886049

RESUMO

The aim of the study was to reveal the difference in the hematological reaction to the applied exercise-induced workload between the able-bodied and physically active people with cervical spinal cord injury. The study covered 11 males with spinal cord injury and 11 able-bodied persons. An incremental stress test was carried out until the maximum individual workloads were achieved. The peak oxygen uptake was measured with the use of the ergospirometric method. Venous blood test results at rest and after finishing the maximal exercise showed hemoglobin (Hb) concentration, hematocrit (HCT) value, erythrocytes (RBC), leukocytes (WBC) and platelets (PLT) counts as well as the relative percentage of granulocytes (GRA), lymphocytes (LYM), and monocytes (MON). RBC, HCT as well as Hb and PLT among people with the injury were statistically lower (p < 0.001) large effect size, than in the control group. Statistically significant difference between the test and control group, subjected to the maximal exercise stress test, was observed in the exercise induced change of the PLT [p < 0.001, (ES: 2.631)] WBC [p < 0.05, (ES: 1.429)] and the percentage of LYM and GRA [p < 0.05, (ES: 1.447) for LYM and (ES: 1.332) for GRA] between both groups, subjected to the maximal cardiac stress test on the manual cycloergometer. The analysis of the obtained results indicates that people with spinal cord injury are much more vulnerable to the occurrence of microcytic anemia compared to able-bodied people. The after-exercise percentage shift of selected subpopulations of leukocytes in both groups indicates a delayed post-exercise recovery among people with spinal cord injury.


Assuntos
Exercício Físico , Traumatismos da Medula Espinal , Eletrocardiografia , Teste de Esforço , Terapia por Exercício , Humanos , Masculino
14.
Artigo em Inglês | MEDLINE | ID: mdl-34360097

RESUMO

The aim of this study was to analyze selected indicators of oxidative stress. The study subjects consisted of 42 women with Hashimoto's disease and a control group of 30 healthy women. The concentration of zinc (Zn) and copper (Cu) in the serum was determined by Atomic Absorption Spectrometry (AAS) and the total antioxidative potential by the Ferric Reducing Ability of Plasma (FRAP) method. In addition, an assessment of concentrations of thiobarbituric acid reactive substances (TBARS) and total phenolics was carried out. Our research showed a significant difference in TBARS concentration (p < 0.0001 (ES: 0.92)) without significant differences in Zn, Cu, FRAP and total phenolics concentrations. Analysis of the correlation of the obtained results of biochemical tests for both groups showed a highly significant dependence of FRAP and total phenolics concentration in the blood of the examined women (r = 0.5283, p = 0.0003). The obtained results indicate no differences in Cu, Zn, and FRAP concentrations in the blood between two analyzed groups and a significantly higher concentration of TBARS in Hashimoto's thyroiditis women. The concentration of total phenolics significantly influences the value of the FRAP.


Assuntos
Cobre , Doença de Hashimoto , Antioxidantes , Feminino , Humanos , Soro , Zinco
15.
Artigo em Inglês | MEDLINE | ID: mdl-33919352

RESUMO

The achievement of high performance levels in a complex structured sport such as karate is determined by the competitor's physical fitness, fighting technique, tactics and mental state. This study aimed to identify the most important determinants of top-level performance in karate. METHODS: The participants were 32 karate competitors (12 women and 20 men) aged 18-25 years. A series of tests measuring 11 anthropometric features was undertaken twice during a year, separated by a 6-week interval during a training camp at the Olympic Preparation Center in Walcz, Poland. Motor skills were measured with strength, speed, endurance, flexibility and reaction time tests. Special motor fitness was assessed with tests of karate technical skills. The results were subject to statistical analysis using multiple stepwise regression of the Polish Karate Federation ranking points as the dependent variable. RESULTS: The multiple regression analysis revealed two main determinants of high scores in female and male karate competitors. In women, these were thigh circumference and the speed of the mawashi-geri-kick roundhouse technique (i.e., the maximum number of delivered kicks in 30 s), whilst for men they were the extent of the sideway leg swing to the highest possible height (yoko-geri) and general endurance assessed with the bent arm hang test. CONCLUSION: Karate training should account for the determinants of high-level competitive karate performance identified in this study. Strengthening the lower limbs, exercises increasing hip joint mobility, low position movements, performing leg techniques in various planes and applying external loads undoubtedly increase a karate athlete's strength and lead to the development of a more extensive repertoire of karate leg techniques, especially at the highest-scoring head level (jodan).


Assuntos
Artes Marciais , Adolescente , Adulto , Antropometria , Feminino , Humanos , Masculino , Destreza Motora , Movimento , Polônia , Adulto Jovem
16.
J Hum Kinet ; 79: 87-99, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34400989

RESUMO

The aim of the research was to present the importance of measuring the impulse of force in assessing exercise capacity in professional rowers and canoeists rather than conducting traditional physiological and biochemical analyses. A group of 20 athletes (12 rowers and 8 canoeists) underwent progressive intensity exercise tests in two testing sessions (before and after a training period). During the tests, maximal aerobic capacity, impulse of strength, metabolic indices, and markers of skeletal muscle damage were assessed. Total testosterone, free testosterone, cortisol, interleukin 1,6, and creatine kinase were evaluated in venous blood. The impulse of force at the ventilatory threshold and at the maximum load was correlated with free testosterone and a total testosterone/cortisol ratio during exercise (p ≤ 0.05) and was negatively correlated with cortisol concentration (p ≤ 0.05) in the first testing session (before training intervention). Values were positively correlated with concentration of total testosterone, free testosterone and total testosterone/cortisol, and free testosterone/cortisol ratios during exercise (p ≤ 0.05) in the second testing session (after training intervention). Biochemical indices of overtraining were correlated with maximum oxygen uptake in each session and with the impulse of force at the ventilatory threshold and the maximum load of exercise. Thus, there is an indirect relationship between maximal aerobic capacity and the impulse of force. The measurement of the impulse of force can become a simple and effective method for evaluating the overall exercise capacity of rowers because of its relationship with indices of the load and changes in hormonal indices of anabolic and catabolic processes during exercise. Therefore, it may constitute a replacement for the traditional laboratory measurement of VO2max in highly qualified rowers and canoeists.

17.
Artigo em Inglês | MEDLINE | ID: mdl-33802129

RESUMO

The objective of this study was to assess the effect of 8-week long endurance training on the prooxidative-antioxidative status of plasma in women treated for breast cancer. The participants of the study were 12 women after radical mastectomy aged 45 to 56 years (M = 50.6 ± 2.9 years), who had undergone full cancer treatment, on average more than 5 years after the treatment (M = 5.9 ± 0.9 years). Body mass components were measured twice using the method of bioelectric impedance analysis. In order to optimize training loads and to assess the level of exercise tolerance of the participants, the group was subject to an ergospirometric exercise test twice, before (1st) and after (2nd) the completion of the training cycle. The blood was also taken twice for biochemical analyses. Statistically significant differences were noted in the maximum exercise load, the level of which increased in the second test (p < 0.05). No change was observed in the level of antioxidative potential, i.e., the content of some variables, ferric reducing ability of plasma (FRAP), urea, total phenolics, thiobarbituric acid reactive substances (TBARS), and in the blood indices of the body's nutritional status during the project (total protein, albumin. Endurance training caused an increase in exercise tolerance and did not cause an aggravation of oxidative stress in women undergoing breast cancer treatment.


Assuntos
Neoplasias da Mama , Treino Aeróbico , Antioxidantes , Neoplasias da Mama/terapia , Feminino , Humanos , Mastectomia , Pessoa de Meia-Idade , Estresse Oxidativo , Resistência Física , Projetos Piloto , Substâncias Reativas com Ácido Tiobarbitúrico
18.
Pediatr Endocrinol Diabetes Metab ; 27(4): 237-244, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-35114764

RESUMO

INTRODUCTION: Monitoring physical activity is a very important issue, especially in type 1 diabetes. One of the parameters assessing the intensity of exercise is the concentration of lactate in the blood. Aim of the study We assessed the intensity of PE and changes in lactate levels in children and adolescents with type 1 diabetes (T1D) during a football tournament. MATERIAL AND METHODS: We enrolled 141 participants, the results of 70 of whom were analyzed, playing in two age categories: 10-13 and 14-17 years. Lactate levels were measured in the capillary blood before and after matches. Blood lactate of 4 mmol/l (Onset Blood Lactate Accumulation OBLA) was used as parameter indicating the prevalence of anaerobic metabolic changes. RESULTS: The median lactate level was 1.8 mmol/l before and 4.4 mmol/l after matches (p < 0.001). The increase in lactate levels was higher in the older age category (4.3 vs. 1.8, p = 0.001) and was independent on gender (3.2 vs. 2.1, p = 0.597), personal insulin pump vs insulin pen use (3.0 vs. 1.5, p = 0.145) or training in a sports club (1.4 vs. 3.0, p = 0.084). A positive correlation was noted between increased lactate levels and age (Rs = 0.253, p = 0.034). 61% of the participants exceeded lactate levels ≥ 4 mmol/l. In univariate logistic regression analysis age was a significantly associated with lactate level ≥ 4 mmol/l [OR = 1.45 (1.08-1.95)] independent of HbA1c, gender, treatment method and training in a sports club. CONCLUSIONS: PE intensity levels during football matches were found to be mixed aerobic-anaerobic. Increases in lactate levels were greater in the older subjects independently on the assessed factors.


Assuntos
Diabetes Mellitus Tipo 1 , Futebol Americano , Adolescente , Criança , Diabetes Mellitus Tipo 1/tratamento farmacológico , Exercício Físico , Humanos , Sistemas de Infusão de Insulina , Ácido Láctico/uso terapêutico
19.
Artigo em Inglês | MEDLINE | ID: mdl-33801780

RESUMO

Long-term insulin treatment can slow the growth process and decrease physical fitness level in children. In diabetic children, these two developments should be constantly monitored. The aim of the present study was to examine differences in somatic and physical fitness characteristics between soccer-training boys with type 1 diabetes and healthy boys of the same age (reference values based on Polish population norms for somatic and motor parameters). The participants were 94 boys (8-17 years), diagnosed with diabetes, who participated in soccer training on a regular basis and received routine medical care. The study involved (a) anthropometric and body composition measurements, (b) general motor ability assessments, and (c) comparison of those characteristics with the healthy Polish population. The diabetic boys were found to have lower levels of almost all somatic traits and motor abilities as compared with the healthy boys (p ≤ 0.05). Handgrip strength was a variable with the smallest difference between the two groups. The observed differences indicate the necessity to design an appropriate control and assessment system based on simple medical and fitness field tests for diabetic children and adolescents. It will allow optimizing advanced training as well as minimize health risks before, during, or after exercise.


Assuntos
Diabetes Mellitus Tipo 1 , Insulinas , Futebol , Adolescente , Criança , Diabetes Mellitus Tipo 1/tratamento farmacológico , Força da Mão , Humanos , Masculino , Aptidão Física , Polônia
20.
Front Aging Neurosci ; 12: 586286, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33192480

RESUMO

Late adulthood is associated with atrophy of brain areas, which contribute to cognitive deterioration and increase the risk of depression. On the other hand, aerobic exercise can improve learning and memory function, ameliorate mood, and prevent neurodegenerative changes. This study demonstrates the effect of Nordic walking (NW) and NW with poles with an integrated resistance shock absorber (NW with RSA) on aerobic capacity and body composition in postmenopausal women. It also measures the brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) serum levels and determines correlations with cognitive functions and depression symptoms. These relationships with the use of NW with RSA as a new form of exercise have not been described thus far. In this study, 31 women (NW - 16, NW with RSA - 15) participated in eight weeks of training. The findings showed that only NW with RSA training caused a significant decrease in body mass and body mass index (p < 0.05). There were no significant changes in GDNF levels between groups studied. Regarding BDNF, a significant decrease (p < 0.05) in the NW group and an increase (not statistically significant) in the NW with RSA group was found. A comparative analysis of cognitive and depression outcomes and changes in BDNF and GDNF concentration showed no significant differences in the efficacy of either form of training. Training loads resulted in a significant increase in VO2max in both the NW (p < 0.01) and NW with RSA (p < 0.05) groups. This indicates an improvement in cardiopulmonary efficiency of the examined women.

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