Detalhe da pesquisa
1.
Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.
Invest New Drugs
; 36(6): 1006-1015, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29728897
2.
PA401, a novel CXCL8-based biologic therapeutic with increased glycosaminoglycan binding, reduces bronchoalveolar lavage neutrophils and systemic inflammatory markers in a murine model of LPS-induced lung inflammation.
Cytokine
; 76(2): 433-441, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26303011
3.
Integration of efficacy, pharmacokinetic and safety assessment of interleukin-1 receptor antagonist in a preclinical model of arthritis.
Regul Toxicol Pharmacol
; 59(3): 461-70, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300126
4.
Population Pharmacokinetics of MCLA-128, a HER2/HER3 Bispecific Monoclonal Antibody, in Patients with Solid Tumors.
Clin Pharmacokinet
; 59(7): 875-884, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32006223
5.
MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis.
Expert Opin Biol Ther
; 19(7): 721-733, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31286786
6.
Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages.
Int Immunopharmacol
; 6(1): 1-7, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16332507
7.
The influence of microbial metabolites on human intestinal epithelial cells and macrophages in vitro.
FEMS Immunol Med Microbiol
; 45(2): 183-9, 2005 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15939578
8.
In search of secreted protein biomarkers for the anti-inflammatory effect of beta2-adrenergic receptor agonists: application of DIGE technology in combination with multivariate and univariate data analysis tools.
J Proteome Res
; 4(6): 2015-23, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16335946