Detalhe da pesquisa
1.
Application of rational enzyme engineering in a new route to etonogestrel and levonorgestrel: carbonyl reductase bioreduction of ethyl secodione.
Faraday Discuss
; 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38864241
2.
Why the Flavin Adenine Dinucleotide (FAD) Cofactor Needs To Be Covalently Linked to Complexâ II of the Electron-Transport Chain for the Conversion of FADH2 into FAD.
Chemistry
; 24(20): 5246-5252, 2018 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29124817
3.
Spatial requirement for PAMO for transformation of non-native linear substrates.
Phys Chem Chem Phys
; 20(4): 2558-2570, 2018 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29318252
4.
Catalytic mechanism of phenylacetone monooxygenases for non-native linear substrates.
Phys Chem Chem Phys
; 19(39): 26851-26861, 2017 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28951930
5.
Evolution of the active site of human glutathione transferase A2-2 for enhanced activity with dietary isothiocyanates.
Biochim Biophys Acta
; 1850(4): 742-9, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25542299
6.
Structural and Functional Impact of Parkinson Disease-Associated Mutations in the E3 Ubiquitin Ligase Parkin.
Hum Mutat
; 36(8): 774-86, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25939424
7.
Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin.
PLoS Comput Biol
; 10(11): e1003935, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25375667
8.
A breakthrough on Amanita phalloides poisoning: an effective antidotal effect by polymyxin B.
Arch Toxicol
; 89(12): 2305-23, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26385100
9.
A multiscale approach to predicting affinity changes in protein-protein interfaces.
Proteins
; 82(10): 2681-90, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24975440
10.
Isomerization of Δ5-androstene-3,17-dione into Δ4-androstene-3,17-dione catalyzed by human glutathione transferase A3-3: a computational study identifies a dual role for glutathione.
J Phys Chem A
; 118(31): 5790-800, 2014 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24739064
11.
Mechanism of glutathione transferase P1-1-catalyzed activation of the prodrug canfosfamide (TLK286, TELCYTA).
Biochemistry
; 52(45): 8069-78, 2013 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24066958
12.
Multidimensional epistasis and fitness landscapes in enzyme evolution.
Biochem J
; 445(1): 39-46, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22533640
13.
SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations.
Biochim Biophys Acta Gen Subj
; 1864(1): 129440, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31536751
14.
Mammalian cytosolic glutathione transferases.
Curr Protein Pept Sci
; 9(4): 325-37, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18691123
15.
Insights from engineering the Affibody-Fc interaction with a computational-experimental method.
Protein Eng Des Sel
; 30(9): 593-601, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472513
16.
Modeling and fitting protein-protein complexes to predict change of binding energy.
Sci Rep
; 6: 25406, 2016 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27173910
17.
New in silico insights into the inhibition of RNAP II by α-amanitin and the protective effect mediated by effective antidotes.
J Mol Graph Model
; 51: 120-7, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24879323
18.
Glutathione transferase classes alpha, pi, and mu: GSH activation mechanism.
J Phys Chem B
; 114(40): 12972-80, 2010 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20853826
19.
Glutathione transferase A1-1: catalytic importance of arginine 15.
J Phys Chem B
; 114(4): 1690-7, 2010 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20052987
20.
Glutathione transferase: new model for glutathione activation.
Chemistry
; 14(31): 9591-8, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18792041