Detalhe da pesquisa
1.
GLP-1-directed NMDA receptor antagonism for obesity treatment.
Nature
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38750368
2.
Epinephrine and glucose regulation of leptin synthesis and secretion in a teleost fish, the tilapia (Oreochromis mossambicus).
Gen Comp Endocrinol
; 302: 113669, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242479
3.
Control of leptin by metabolic state and its regulatory interactions with pituitary growth hormone and hepatic growth hormone receptors and insulin like growth factors in the tilapia (Oreochromis mossambicus).
Gen Comp Endocrinol
; 240: 227-237, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27449341
4.
Leptin stimulates hepatic growth hormone receptor and insulin-like growth factor gene expression in a teleost fish, the hybrid striped bass.
Gen Comp Endocrinol
; 229: 84-91, 2016 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26853487
5.
Prolactin is a major inhibitor of hepatic Leptin A synthesis and secretion: studies utilizing a homologous Leptin A ELISA in the tilapia.
Gen Comp Endocrinol
; 207: 86-93, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24662392
6.
The GLP-1R as a model for understanding and exploiting biased agonism in next-generation medicines.
J Endocrinol
; 261(2)2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38451873
7.
Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice.
Mol Metab
; 83: 101915, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38492844
8.
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.
Nat Metab
; 5(6): 945-954, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277609
9.
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice.
Nat Metab
; 5(12): 2075-2085, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37946085
10.
GLP-1/GIP/glucagon receptor triagonism gets its try in humans.
Cell Metab
; 34(1): 3-4, 2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34986336
11.
Ildr1 gene deletion protects against diet-induced obesity and hyperglycemia.
PLoS One
; 17(6): e0270329, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35749484
12.
Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice.
Mol Metab
; 63: 101533, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35809773
13.
Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems.
Mol Metab
; 66: 101638, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36400403
14.
Optimization of Truncated Glucagon Peptides to Achieve Selective, High Potency, Full Antagonists.
J Med Chem
; 64(8): 4697-4708, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33821647
15.
The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition.
Diabetes
; 69(5): 882-892, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005706
16.
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.
JCI Insight
; 5(17)2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32730231
17.
The Effects of Bariatric Surgery on Islet Function, Insulin Secretion, and Glucose Control.
Endocr Rev
; 40(5): 1394-1423, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31241742
18.
Temporal plasticity of insulin and incretin secretion and insulin sensitivity following sleeve gastrectomy contribute to sustained improvements in glucose control.
Mol Metab
; 28: 144-150, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31326351
19.
Sleeve gastrectomy rapidly enhances islet function independently of body weight.
JCI Insight
; 4(6)2019 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30777938
20.
Leptin Stimulates Cellular Glycolysis Through a STAT3 Dependent Mechanism in Tilapia.
Front Endocrinol (Lausanne)
; 9: 465, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30186233