Detalhe da pesquisa
1.
Disruption of a ciliary B9 protein complex causes Meckel syndrome.
Am J Hum Genet
; 89(1): 94-110, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21763481
2.
Role of epidermal primary cilia in the homeostasis of skin and hair follicles.
Development
; 138(9): 1675-85, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21429982
3.
Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques.
Nat Biotechnol
; 42(3): 413-423, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156915
4.
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases.
J Med Chem
; 67(7): 5758-5782, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38511649
5.
A high-fat diet regulates gastrin and acid secretion through primary cilia.
FASEB J
; 26(8): 3127-39, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22516298
6.
Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice.
Nat Commun
; 14(1): 2020, 2023 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037829
7.
Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice.
Sci Transl Med
; 15(691): eadg5794, 2023 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37043559
8.
SUPT4H1 Depletion Leads to a Global Reduction in RNA.
Cell Rep
; 26(1): 45-53.e4, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30605685
9.
Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD.
Neuron
; 103(5): 802-819.e11, 2019 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31272829
10.
Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9.
Cell Rep
; 20(10): 2341-2356, 2017 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28877469
11.
Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo.
ACS Med Chem Lett
; 7(1): 72-6, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26819669
12.
TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone.
J Cell Biol
; 209(1): 129-42, 2015 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25869670
13.
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Nat Cell Biol
; 16(11): 1069-79, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25327288
14.
Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms.
Nat Cell Biol
; 10(1): 70-6, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18084282