Detalhe da pesquisa
1.
Development of dietary soluble fibres by enzymatic synthesis and assessment of their digestibility in in vitro, animal and randomised clinical trial models.
Int J Food Sci Nutr
; 68(7): 849-864, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28276900
2.
Current Therapeutic Landscape and Safety Roadmap for Targeting the Aryl Hydrocarbon Receptor in Inflammatory Gastrointestinal Indications.
Cells
; 11(10)2022 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35626744
3.
Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity.
ALTEX
; 39(4): 560-582, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35502629
4.
New phenotypic cytotoxicity assay for ROS-inducing compounds using rat renal epithelial cells.
Toxicol Lett
; 331: 227-234, 2020 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32522578
5.
Rat toxicogenomic study reveals analytical consistency across microarray platforms.
Nat Biotechnol
; 24(9): 1162-9, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17061323
6.
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.
Nat Biotechnol
; 24(9): 1151-61, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16964229
7.
Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury.
Toxicol Sci
; 167(2): 458-467, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30289550
8.
Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS.
J Chromatogr B Analyt Technol Biomed Life Sci
; 871(2): 328-40, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18472313
9.
Self-self hybridization as an alternative experiment design to dye swap for two-color microarrays.
OMICS
; 11(1): 14-24, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17411393
10.
Fasiglifam (TAK-875) Alters Bile Acid Homeostasis in Rats and Dogs: A Potential Cause of Drug Induced Liver Injury.
Toxicol Sci
; 157(1): 50-61, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28108665
11.
Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists.
BMC Bioinformatics
; 7 Suppl 2: S18, 2006 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-17118139
12.
An integrated study of acute effects of valproic acid in the liver using metabonomics, proteomics, and transcriptomics platforms.
OMICS
; 10(1): 1-14, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16584314
13.
Mode of action in relevance of rodent liver tumors to human cancer risk.
Toxicol Sci
; 89(1): 51-6, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16221960
14.
Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency.
Mutat Res
; 593(1-2): 80-7, 2006 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16144704
15.
Human induced pluripotent stem cells and their use in drug discovery for toxicity testing.
Toxicol Lett
; 219(1): 49-58, 2013 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23470867
16.
Cellular impedance assays for predictive preclinical drug screening of kinase inhibitor cardiovascular toxicity.
Toxicol Sci
; 135(2): 402-13, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23897988
17.
Evaluation of cellular impedance measures of cardiomyocyte cultures for drug screening applications.
Assay Drug Dev Technol
; 10(6): 525-32, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22574652
18.
What do we need to know prior to thinking about incorporating an epigenetic evaluation into safety assessments?
Toxicol Sci
; 116(2): 375-81, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20430866
19.
Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells.
Mol Divers
; 10(3): 349-60, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17031537
20.
Improved cell typing by charge-state deconvolution of matrix-assisted laser desorption/ionization mass spectra.
Rapid Commun Mass Spectrom
; 20(10): 1595-603, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16628570