Detalhe da pesquisa
1.
Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus.
J Immunol
; 207(1): 34-43, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34108258
2.
Identification and stratification of systemic lupus erythematosus patients into two transcriptionally distinct clusters based on IFN-I signature.
Lupus
; 30(5): 762-774, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33497307
3.
Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity.
J Immunol
; 198(3): 1308-1319, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003376
4.
Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology.
ACS Med Chem Lett
; 15(2): 189-196, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38352849
5.
Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
ACS Med Chem Lett
; 15(2): 181-188, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38352830
6.
Identification of 2-Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8).
ACS Med Chem Lett
; 13(5): 812-818, 2022 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35586440
7.
CD80 blockade enhance glucocorticoid-induced leucine zipper expression and suppress experimental autoimmune encephalomyelitis.
J Immunol
; 183(11): 7505-13, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19917693
8.
Anti-inflammatory activity of edible oyster mushroom is mediated through the inhibition of NF-κB and AP-1 signaling.
Nutr J
; 10: 52, 2011 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21575254
9.
Azatricyclic Inverse Agonists of RORγt That Demonstrate Efficacy in Models of Rheumatoid Arthritis and Psoriasis.
ACS Med Chem Lett
; 12(5): 827-835, 2021 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34055233
10.
Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction.
JACC Basic Transl Sci
; 6(8): 676-689, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34466754
11.
Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9).
ACS Med Chem Lett
; 11(9): 1751-1758, 2020 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32944143
12.
Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds.
J Sep Sci
; 32(23-24): 4052-8, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19937965
13.
Diminished responses to monoaminergic antidepressants but not ketamine in a mouse model for neuropsychiatric lupus.
J Psychopharmacol
; 33(1): 25-36, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484737
14.
Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.
Eur J Pain
; 11(5): 528-34, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16920373
15.
Bruton's tyrosine kinase inhibitor BMS-986142 in experimental models of rheumatoid arthritis enhances efficacy of agents representing clinical standard-of-care.
PLoS One
; 12(7): e0181782, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28742141
16.
Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats.
Eur J Pharmacol
; 530(1-2): 59-69, 2006 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-16364289
17.
Role of oxidative stress in pathophysiology of peripheral neuropathy and modulation by N-acetyl-L-cysteine in rats.
Eur J Pain
; 10(7): 573-9, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16214382
18.
Synergistic anti-inflammatory interaction between meloxicam and aminoguanidine hydrochloride in carrageenan-induced acute inflammation in rats.
Life Sci
; 78(10): 1044-8, 2006 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16109432
19.
Interaction of inducible nitric oxide synthase and cyclooxygenase-2 inhibitors in formalin-induced nociception in mice.
Eur J Pharmacol
; 492(2-3): 117-22, 2004 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15178354
20.
Therapeutic potential of chloroquine in a murine model of inflammatory bowel disease.
Int Immunopharmacol
; 21(2): 328-35, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24859061