Detalhe da pesquisa
1.
Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4.
Nucleic Acids Res
; 47(11): 5973-5987, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31066441
2.
2'-Deoxyribonucleoside 5'-triphosphates bearing 4-phenyl and 4-pyrimidinyl imidazoles as DNA polymerase substrates.
Org Biomol Chem
; 17(2): 290-301, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30543241
3.
Structural analysis of the Trypanosoma brucei EIF4E6/EIF4G5 complex reveals details of the interaction between unusual eIF4F subunits.
Sci Rep
; 14(1): 2178, 2024 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38272944
4.
From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus.
ACS Infect Dis
; 6(3): 422-435, 2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32017533
5.
First-in-class allosteric inhibitors of bacterial IMPDHs.
Eur J Med Chem
; 167: 124-132, 2019 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30769241
6.
Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives -- a screening based on affinity for the UMP-CMP binding site.
FEBS J
; 274(14): 3704-3714, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17608725
7.
Looking for new pyrimidine acyclic nucleotide analogues designed for phosphorylation by human UMP-CMP kinase.
Nucleosides Nucleotides Nucleic Acids
; 26(10-12): 1369-73, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18066785
8.
Recognition of nucleotide analogs containing the 7,8-dihydro-8-oxo structure by the human MTH1 protein.
J Biochem
; 140(6): 843-9, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17071637
9.
Synthesis and recognition by DNA polymerases of a reactive nucleoside, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-imidazole-4-hydrazide.
Nucleic Acids Res
; 30(9): 1869-78, 2002 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11972322
10.
Substrate specificity of vaccinia virus thymidylate kinase.
FEBS J
; 272(24): 6254-65, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16336263
11.
Probing the substrate recognition mechanism of the human MTH1 protein by nucleotide analogs.
J Mol Biol
; 336(4): 843-50, 2004 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-15095864
12.
3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
J Med Chem
; 46(18): 3811-21, 2003 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12930144
13.
Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.
Structure
; 20(6): 1107-17, 2012 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22608967
14.
Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4
Artigo
em Português
| ARCA | ID: arc-36012
15.
Expanding substrate specificity of nucleoside 2'-deoxyribosyltransferase.
Nucleic Acids Symp Ser (Oxf)
; (52): 495-6, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18776470
16.
In vivo reshaping the catalytic site of nucleoside 2'-deoxyribosyltransferase for dideoxy- and didehydronucleosides via a single amino acid substitution.
J Biol Chem
; 283(29): 20053-9, 2008 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18487606
17.
A parallel synthesis scheme for generating libraries of DNA polymerase substrates and inhibitors.
Chembiochem
; 3(12): 1251-6, 2002 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12465034
18.
Substrate recognition by the human MTH1 protein.
Nucleic Acids Res Suppl
; (2): 85-6, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12903117
19.
Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.
Chembiochem
; 4(8): 742-7, 2003 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12898625
20.
Nucleoside analogues as inhibitors of thymidylate kinases: possible therapeutic applications.
Chembiochem
; 3(1): 108-10, 2002 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-17590962