Detalhe da pesquisa
1.
Incidence, Risk Factors, and Clinical Consequence of Enteral Feeding Intolerance in the Mechanically Ventilated Critically Ill: An Analysis of a Multicenter, Multiyear Database.
Crit Care Med
; 49(1): 49-59, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33148950
2.
Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study.
Lancet
; 389(10074): 1114-1123, 2017 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28187915
3.
A randomized, double-blind, placebo-controlled trial of camicinal in Parkinson's disease.
Mov Disord
; 33(2): 329-332, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29278279
4.
BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial.
BMC Gastroenterol
; 16(1): 71, 2016 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27431238
5.
The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial.
Crit Care
; 20(1): 232, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27476581
6.
Genetic variants in CDC42 and NXPH1 as susceptibility factors for constipation and diarrhoea predominant irritable bowel syndrome.
Gut
; 63(7): 1103-11, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24041540
7.
Impaired emotional learning and involvement of the corticotropin-releasing factor signaling system in patients with irritable bowel syndrome.
Gastroenterology
; 145(6): 1253-61.e1-3, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23954313
8.
Identifying and testing candidate genetic polymorphisms in the irritable bowel syndrome (IBS): association with TNFSF15 and TNFα.
Gut
; 62(7): 985-94, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22684480
9.
A randomized phase 2 study of the 5-HT4 receptor agonist felcisetrag for postoperative gastrointestinal dysfunction after bowel surgery.
Am J Surg
; 2024 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38724293
10.
Incidence and risk factors for postoperative gastrointestinal dysfunction occurrence after gastrointestinal procedures in US patients.
Am J Surg
; 226(5): 675-681, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37479563
11.
Corticotropin-releasing factor receptor 1 antagonist alters regional activation and effective connectivity in an emotional-arousal circuit during expectation of abdominal pain.
J Neurosci
; 31(35): 12491-500, 2011 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21880911
12.
The Effect of Hepatic Impairment on the Pharmacokinetics of Intravenously Administered Felcisetrag (TAK-954).
J Clin Pharmacol
; 62(8): 1006-1017, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35253917
13.
Evaluation of the pharmacokinetics of trazpiroben (TAK-906) in the presence and absence of the proton pump inhibitor esomeprazole.
Clin Transl Sci
; 15(5): 1281-1290, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35218604
14.
The pharmacokinetics of oral trazpiroben (TAK-906) after organic anion transporting polypeptide 1B1/1B3 inhibition: A phase I, randomized study.
Clin Transl Sci
; 15(6): 1532-1543, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35460165
15.
Distinct neurophysiological profiles in irritable bowel syndrome.
Am J Physiol Gastrointest Liver Physiol
; 300(6): G1086-93, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21350185
16.
A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients.
Pharm Res
; 28(2): 394-404, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20949310
17.
Randomised clinical trial: safety, pharmacokinetics and pharmacodynamics of trazpiroben (TAK-906), a dopamine D2 /D3 receptor antagonist, in patients with gastroparesis.
Aliment Pharmacol Ther
; 54(3): 267-280, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34148244
18.
Randomised study: effects of the 5-HT4 receptor agonist felcisetrag vs placebo on gut transit in patients with gastroparesis.
Aliment Pharmacol Ther
; 53(9): 1010-1020, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33711180
19.
Neurophysiological evaluation of convergent afferents innervating the human esophagus and area of referred pain on the anterior chest wall.
Am J Physiol Gastrointest Liver Physiol
; 298(1): G31-6, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20023227
20.
Irritable bowel syndrome: more than abdominal pain and bowel habit abnormalities.
Clin Gastroenterol Hepatol
; 7(1): 73-9, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19124114