Mindfulness Meditation and Psychopathology.

Mindfulness meditation is increasingly incorporated into mental health interventions, and theoretical concepts associated with it have influenced basic research on psychopathology. Here, we review the current understanding of mindfulness meditation through the lens of clinical neuroscience, outlining the core capacities targeted by mindfulness meditation and mapping them onto cognitive and affective constructs of the Research Domain Criteria matrix proposed by the National Institute of Mental Health. We review efficacious applications of mindfulness meditation to specific domains of psychopathology including depression, anxiety, chronic pain, and substance abuse, as well as emerging efforts related to attention disorders, traumatic stress, dysregulated eating, and serious mental illness. Priorities for future research include pinpointing mechanisms, refining methodology, and improving implementation. Mindfulness meditation is a promising basis for interventions, with particular potential relevance to psychiatric comorbidity. The successes and challenges of mindfulness meditation research are instructive for broader interactions between contemplative traditions and clinical psychological science.

Visualizing Compassion: Episodic Simulation as Contemplative Practice.

Contemplative interventions designed to cultivate compassion are receiving increasing empirical attention. Accumulating evidence suggests that these interventions bolster prosocial motivation and warmth towards others. Less is known about how these practices impact compassion in everyday life. Here we consider one mechanistic pathway through which compassion practices may impact perception and action in the world: simulation. Evidence suggests that vividly imagining a situation simulates that experience in the brain as if it were, to a degree, actually happening. Thus, we hypothesize that simulation during imagery-based contemplative practices can construct sensorimotor patterns in the brain that prime an individual to act compassionately in the world. We first present evidence across multiple literatures in Psychology that motivates this hypothesis, including the neuroscience of mental imagery and the emerging literature on prosocial episodic simulation. Then, we examine the specific contemplative practices in compassion-based interventions that may construct such simulations. We conclude with future directions for investigating how compassion-based interventions may shape prosocial perception and action in everyday life.

Does variability across three universities in the implementation of a college course on human flourishing affect student outcomes?

OBJECTIVE: This study explores whether variability in the implementation of an undergraduate course on human flourishing is differentially associated with student outcomes. PARTICIPANTS: 101 students in the "Art and Science of Human Flourishing" course across three large, public, R1 universities in Fall 2018 participated in the study. METHODS: Formative course data included researcher observations of weekly class pedagogy, students' weekly meditation practice logs and end-of-course assessments, and pre/post surveys measuring changes in participating students' outcomes related to flourishing (e.g., attentional skills, social-emotional skills, perspectives on flourishing, mental and physical health). RESULTS: Although course pedagogy and student engagement varied across the three universities, students' outcomes were nonetheless similar. CONCLUSIONS: Variability in course implementation did not appear to differentially affect students' outcomes. We tentatively conclude that other institutions interested in offering the flourishing course may make limited adaptations to fit their pedagogical preferences without concern for altering its impact on students.

Can the Academic and Experiential Study of Flourishing Improve Flourishing in College Students? A Multi-University Study.

Objectives: Significant concerns have been raised about the "mental health crisis" on college campuses, with attention turning to what colleges can do beyond counseling services to address students' mental health and well-being. We examined whether primarily first-year (89.1%) undergraduate students (n=651) who enrolled in the Art and Science of Human Flourishing (ASHF), a novel academic and experiential for-credit elective course on human flourishing, would demonstrate improved mental health and strengthen skills, perspectives, and behaviors associated with flourishing relative to students who did not enroll in this course. Methods: In a two-wave, multi-site, propensity-score matched controlled trial (ASHF n=217, Control n=434; N=651), we used hierarchal linear models and false discovery rate corrected doubly robust estimates to evaluate the impact of the ASHF on attention and social-emotional skill development, flourishing perspectives, mental health, health, and risk behavior outcomes. Results: ASHF participants reported significantly improved mental health (i.e., reduced depression) and flourishing, improvements on multiple attention and social-emotional skills (e.g., attention function, self-compassion), and increases in prosocial attitudes (empathic concern, shared humanity; Cohen's ds= 0.18-0.46) compared to controls. There was no evidence for ASHF course impacts on health or risk behaviors, raising the possibility that these outcomes take more time to change. Conclusions: This research provides initial evidence that the ASHF course may be a promising curricular approach to reduce and potentially prevent poor mental health while promoting flourishing in college students. Continued research is needed to confirm these conclusions.

Cultivating Emotional Granularity.

An emerging focus in affective science is the expertise that underlies healthy emotionality. A growing literature highlights emotional granularity - the ability to make fine-grained distinctions in one's affective feelings - as an important skill. Cross-sectional evidence indicating the benefits of emotional granularity raises the question of how emotional granularity might be intentionally cultivated through training. To address this question, we present shared theoretical features of centuries-old Buddhist philosophy and modern constructionist theory that motivate the hypothesis that contemplative practices may improve granularity. We then examine the specific mindfulness-style practices originating in Buddhist traditions that are hypothesized to bolster granularity. We conclude with future directions to empirically test whether emotional granularity can be intentionally cultivated.

No Detectable Electroencephalographic Activity After Clinical Declaration of Death Among Tibetan Buddhist Meditators in Apparent Tukdam, a Putative Postmortem Meditation State.

Recent EEG studies on the early postmortem interval that suggest the persistence of electrophysiological coherence and connectivity in the brain of animals and humans reinforce the need for further investigation of the relationship between the brain's activity and the dying process. Neuroscience is now in a position to empirically evaluate the extended process of dying and, more specifically, to investigate the possibility of brain activity following the cessation of cardiac and respiratory function. Under the direction of the Center for Healthy Minds at the University of Wisconsin-Madison, research was conducted in India on a postmortem meditative state cultivated by some Tibetan Buddhist practitioners in which decomposition is putatively delayed. For all healthy baseline (HB) and postmortem (PM) subjects presented here, we collected resting state electroencephalographic data, mismatch negativity (MMN), and auditory brainstem response (ABR). In this study, we present HB data to demonstrate the feasibility of a sparse electrode EEG configuration to capture well-defined ERP waveforms from living subjects under very challenging field conditions. While living subjects displayed well-defined MMN and ABR responses, no recognizable EEG waveforms were discernable in any of the tukdam cases.

Attention regulation and monitoring in meditation.

Meditation can be conceptualized as a family of complex emotional and attentional regulatory training regimes developed for various ends, including the cultivation of well-being and emotional balance. Among these various practices, there are two styles that are commonly studied. One style, focused attention meditation, entails the voluntary focusing of attention on a chosen object. The other style, open monitoring meditation, involves nonreactive monitoring of the content of experience from moment to moment. The potential regulatory functions of these practices on attention and emotion processes could have a long-term impact on the brain and behavior.

Mindful meta-awareness: sustained and non-propositional.

Meta-awareness appears to be essential to nearly all forms of mindfulness practice, and it plays a key role in processes that are central to therapeutic effects of mindfulness training, including decentering - shifting one's experiential perspective onto an experience itself - and dereification or metacognitive insight - experiencing thoughts as mental events, and not as the things that they seem to represent. Important advances in the conceptualization of meta-awareness in mindfulness have recently been made, yet more clarity is required in order to characterize the type of meta-awareness implicated in the ongoing monitoring of attention and affect, even while attention itself is focused on an explicit object of awareness such as the breath. To enhance research on this form of meta-awareness cultivated in at least some styles of mindfulness, a construct of sustained, non-propositional meta-awareness is proposed.

The next generation of mindfulness-based intervention research: what have we learned and where are we headed?

The previous two decades have seen an exponential increase in the number of published scientific investigations on the efficacy of mindfulness-based stress reduction (MBSR) training to improve function in a wide range of physical and psychological processes. The resulting body of work provides strong evidence that MBSR has salubrious effects. Yet, when compared directly to groups with training that matches MBSR in factors common to most legitimate interventions, such as learning new skills, expectation of benefit, social engagement and support, and attention from expert instructors, both groups tend to improve to a similar extent. This raises the question of whether there are benefits that are specific to training in mindfulness and if so, why are we not detecting them? Here, we discuss the factors that contribute to the general lack of differentiation between MBSR and active control groups, including the specificity of outcome measures and experimental design, random assignment, inclusion/exclusion criteria, and the time course and trajectory of change. In addition, we offer recommendations to address these factors in future research.

When mindfulness is therapy: Ethical qualms, historical perspectives.

In the past 20 years, mindfulness therapeutic programs have moved firmly into the mainstream of clinical practice and beyond. As they have, we have also seen the development of an increasingly vocal critique. At issue is often less whether or not these mindfulness practices "work," and more whether there is a danger in dissociating them from the ethical frameworks for which they were originally developed. Mindfulness, the argument goes, was never supposed to be about weight loss, better sex, helping children perform better in school, helping employees be more productive in the workplace, or even improving the functioning of anxious, depressed people. It was never supposed to be a merchandized commodity to be bought and sold. The larger clinical and religious community, however, has not always been troubled by the idea that (PsycINFO Database Record

Investigating the phenomenological matrix of mindfulness-related practices from a neurocognitive perspective.

There has been a great increase in literature concerned with the effects of a variety of mental training regimes that generally fall within what might be called contemplative practices, and a majority of these studies have focused on mindfulness. Mindfulness meditation practices can be conceptualized as a set of attention-based, regulatory, and self-inquiry training regimes cultivated for various ends, including wellbeing and psychological health. This article examines the construct of mindfulness in psychological research and reviews recent, nonclinical work in this area. Instead of proposing a single definition of mindfulness, we interpret it as a continuum of practices involving states and processes that can be mapped into a multidimensional phenomenological matrix which itself can be expressed in a neurocognitive framework. This phenomenological matrix of mindfulness is presented as a heuristic to guide formulation of next-generation research hypotheses from both cognitive/behavioral and neuroscientific perspectives. In relation to this framework, we review selected findings on mindfulness cultivated through practices in traditional and research settings, and we conclude by identifying significant gaps in the literature and outline new directions for research.