Detalhe da pesquisa
1.
Machine learning approach informs biology of cancer drug response.
BMC Bioinformatics
; 23(1): 184, 2022 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581546
2.
Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.
Proc Natl Acad Sci U S A
; 114(25): E4951-E4960, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28584132
3.
A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells.
BMC Genomics
; 20(1): 497, 2019 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31208320
4.
RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens.
Genome Res
; 26(1): 119-29, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26553456
5.
Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.
Hepatology
; 67(3): 924-939, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28961327
6.
Clonal selection drives genetic divergence of metastatic medulloblastoma.
Nature
; 482(7386): 529-33, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343890
7.
Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function.
Dev Biol
; 414(2): 219-27, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102016
8.
Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms.
Int J Cancer
; 140(4): 853-863, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27790711
9.
The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis.
PLoS Genet
; 9(12): e1003937, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24367269
10.
Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis.
PLoS Genet
; 9(4): e1003441, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23593033
11.
A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model.
Blood
; 121(21): 4355-8, 2013 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23591791
12.
Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer.
J Immunol
; 190(8): 4393-9, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23475219
13.
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.
Proc Natl Acad Sci U S A
; 109(16): 5934-41, 2012 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22421440
14.
Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens.
BMC Genomics
; 15: 1150, 2014 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25526783
15.
Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.
Hepatology
; 57(1): 120-30, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22899566
16.
A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis.
Proc Natl Acad Sci U S A
; 108(14): 5765-70, 2011 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21436051
17.
Single-cell genomics analysis reveals complex genetic interactions in an in vivo model of acquired BRAF inhibitor resistance.
NAR Cancer
; 6(1): zcad061, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38213996
18.
Cell of origin strongly influences genetic selection in a mouse model of T-ALL.
Blood
; 118(17): 4646-56, 2011 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21828136
19.
Understanding cancer drug resistance with Sleeping Beauty functional genomic screens: Application to MAPK inhibition in cutaneous melanoma.
iScience
; 26(10): 107805, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37860756
20.
Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1.
Genesis
; 50(2): 112-8, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21898766