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1.
BMC Pediatr ; 19(1): 93, 2019 04 05.
Artigo em Inglês | MEDLINE | ID: mdl-30953480

RESUMO

BACKGROUND: Total colonic and small bowel aganglionosis (TCSA) occurs in less than 1% of all Hirschsprung's disease patients. Currently, the mainstay of treatment is surgery. However, in patients with TCSA, functional outcomes are often poor. A characteristic transition zone in TCSA can be difficult to identify which may complicate surgery and may often require multiple operations. CASE PRESENTATION: We present the case of a male infant who was diagnosed with biopsy-proven total colonic aganglionosis with extensive small bowel involvement as a neonate. The patient was diverted at one month of age based on leveling biopsies at 10 cm from the Ligament of Treitz. At 7 months of age, during stoma revision for a prolapsed stoma, intra-operative peristalsis was observed in nearly the entire length of the previously aganglionic bowel, and subsequent biopsies demonstrated the appearance of mature ganglion cells in a previously aganglionic segment. CONCLUSIONS: TCSA remains a major challenge for pediatric surgeons. Our case introduces new controversy to our understanding of aganglionosis. Our observations warrant further research into the possibility of post-natal ganglion maturation and encourage surgeons to consider a more conservative surgical approach.


Assuntos
Gânglios/patologia , Doença de Hirschsprung/cirurgia , Intestino Delgado/inervação , Biópsia , Colo/anormalidades , Colo/patologia , Colo/cirurgia , Doença de Hirschsprung/patologia , Humanos , Recém-Nascido , Enteropatias/diagnóstico por imagem , Enteropatias/patologia , Intestino Delgado/diagnóstico por imagem , Intestino Delgado/patologia , Intestino Delgado/cirurgia , Masculino , Radiografia
2.
BMC Pediatr ; 19(1): 172, 2019 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-31138158

RESUMO

Following publication of the original article [1], the authors reported error on the images/figures used which also resulted in un-sequential order. The updated figures and captions are provided below.

3.
Am J Hematol ; 90(3): 187-92, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25382665

RESUMO

The outcomes of children with congenital hemolytic anemia (CHA) undergoing total splenectomy (TS) or partial splenectomy (PS) remain unclear. In this study, we collected data from 100 children with CHA who underwent TS or PS from 2005 to 2013 at 16 sites in the Splenectomy in Congenital Hemolytic Anemia (SICHA) consortium using a patient registry. We analyzed demographics and baseline clinical status, operative details, and outcomes at 4, 24, and 52 weeks after surgery. Results were summarized as hematologic outcomes, short-term adverse events (AEs) (≤30 days after surgery), and long-term AEs (31-365 days after surgery). For children with hereditary spherocytosis, after surgery there was an increase in hemoglobin (baseline 10.1 ± 1.8 g/dl, 52 week 12.8 ± 1.6 g/dl; mean ± SD), decrease in reticulocyte and bilirubin as well as control of symptoms. Children with sickle cell disease had control of clinical symptoms after surgery, but had no change in hematologic parameters. There was an 11% rate of short-term AEs and 11% rate of long-term AEs. As we accumulate more subjects and longer follow-up, use of a patient registry should enhance our capacity for clinical trials and engage all stakeholders in the decision-making process.


Assuntos
Síndrome Torácica Aguda/patologia , Anemia Hemolítica Congênita/cirurgia , Anemia Falciforme/cirurgia , Anquirinas/deficiência , Complicações Pós-Operatórias/patologia , Infecções Respiratórias/patologia , Esferocitose Hereditária/cirurgia , Esplenectomia/métodos , Síndrome Torácica Aguda/etiologia , Adolescente , Anemia Hemolítica Congênita/patologia , Anemia Falciforme/patologia , Bilirrubina/sangue , Criança , Pré-Escolar , Feminino , Hemoglobinas/metabolismo , Humanos , Masculino , Sistema de Registros , Infecções Respiratórias/etiologia , Reticulócitos/patologia , Esferocitose Hereditária/patologia , Resultado do Tratamento , Estados Unidos
4.
Indian J Public Health ; 58(1): 22-6, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24748353

RESUMO

CONTEXT: Birth and immediate postpartum period pose many challenges for the newborn. The neonatal mortality rates are high in India, whereas the breastfeeding rates are still low. Hence, need exists for a simple and easily applicable intervention, which may counter these challenges. AIMS: The present study was undertaken to evaluate the effects of very early skin-to-skin contact (SSC), in term babies with their mothers, on success of breastfeeding and neonatal well-being. SETTINGS AND DESIGN: Randomized control trial conducted over 2 years' period in a tertiary care hospital. MATERIALS AND METHODS: Healthy babies delivered normally were included. Very early SSC between mothers and their newborns was initiated in the study group. We studied effective suckling (using modified infant breastfeeding assessment tool [IBFAT]), breastfeeding status at 6 weeks, maternal satisfaction, thermal regulation, baby's weight and morbidity. STATISTICAL ANALYSIS: T-test, Pearson Chi-square test and non-parametric Mann-Whitney test were used through relevant Windows SPSS software version 16.0. RESULTS: We observed that SSC contributed to better suckling competence as measured by IBFAT score (P < 0.0001). More babies in the SSC group were exclusively breastfed at first follow-up visit (P = 0.002) and at 6 weeks (P < 0.0001). SSC led to higher maternal satisfaction rates, better temperature gain in immediate post-partum period, lesser weight loss was at discharge and at first follow-up (all P < 0.0001) and lesser morbidity than the study group (P = 0.006). CONCLUSION: Very early SSC is an effective intervention that improves baby's suckling competence, maternal satisfaction, breastfeeding rates and temperature control and weight patterns.


Assuntos
Aleitamento Materno/estatística & dados numéricos , Hipotermia/prevenção & controle , Pele , Adulto , Temperatura Corporal , Peso Corporal , Feminino , Humanos , Índia/epidemiologia , Lactente , Recém-Nascido , Masculino , Satisfação Pessoal , Período Pós-Parto/psicologia , Centros de Atenção Terciária/estatística & dados numéricos
5.
Eur Urol Oncol ; 7(1): 63-72, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37516587

RESUMO

BACKGROUND: Men with high-risk prostate cancer undergoing surgery likely recur due to failure to completely excise regional and/or local disease. OBJECTIVE: The first-in-human evaluation of safety, pharmacokinetics, and exploratory efficacy of IS-002, a novel near-infrared prostate-specific membrane antigen (PSMA)-targeted fluorescence imaging agent, designed for intraoperative prostate cancer visualization. DESIGN, SETTING, AND PARTICIPANTS: A phase 1, single-center, dose-escalation study was conducted in 24 men with high-risk prostate cancer scheduled for robotic-assisted radical prostatectomy with (extended) pelvic lymph node dissection using the da Vinci surgical system. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Adverse events (AEs), vital signs, complete blood count, complete metabolic panel, urinalysis, and electrocardiogram were assessed over a 14-d period and compared with baseline. The pharmacokinetic profile of IS-002 was determined. Diagnostic accuracy was assessed for exploratory efficacy. RESULTS AND LIMITATIONS: AEs predominantly included discoloration of urine (n = 22/24; expected, related, grade 1). There were no grade ≥2 AEs. IS-002 Cmax and area under the curve increased with increasing dose. Plasma concentrations declined rapidly in a biphasic manner, with the median terminal half-lives ranging from 5.0 to 7.6 h, independent of dose and renal function. At 25 µg/kg, the exploratory efficacy readouts for the negative and positive predictive values were, 97% and 45% for lymph nodes, and 100% and 80% for residual/locoregional disease detection, respectively. CONCLUSIONS: IS-002 is safe and well tolerated, and has the potential to enable intraoperative tumor detection that could not be identified using standard imaging. PATIENT SUMMARY: IS-002 is a new imaging agent that specifically targets the prostate-specific membrane antigen receptor. In this study, we tested IS-002 for the first time in men with high-risk prostate cancer undergoing surgery and found that IS-002 is safe, is cleared from the body quickly, and potentially allows identification of prostate cancer in areas that would not be identified by conventional white light imaging.


Assuntos
Neoplasias da Próstata , Procedimentos Cirúrgicos Robóticos , Masculino , Humanos , Próstata/patologia , Recidiva Local de Neoplasia/patologia , Neoplasias da Próstata/diagnóstico por imagem , Neoplasias da Próstata/cirurgia , Prostatectomia/métodos
6.
J Emerg Med ; 43(1): e49-51, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22325550

RESUMO

BACKGROUND: Intestinal malrotation in the newborn is usually diagnosed after signs of intestinal obstruction, such as bilious emesis, and corrected with the Ladd procedure. OBJECTIVES: The objective of this report is to describe the presentation of severe cases of midgut volvulus presenting in infancy, and to discuss the characteristics of these cases. CASE REPORT: We performed a 7-year review at our institution and present two cases of catastrophic midgut volvulus presenting in the post-neonatal period, ending in death soon after the onset of symptoms. These two patients also had significant laboratory abnormalities compared to patients with more typical presentations resulting in favorable outcomes. CONCLUSIONS: Although most cases of intestinal malrotation in infancy can be treated successfully, in some circumstances, patients' symptoms may not be detected early enough for effective treatment, and therefore may result in catastrophic midgut volvulus and death.


Assuntos
Volvo Intestinal/congênito , Volvo Intestinal/diagnóstico , Evolução Fatal , Humanos , Lactente , Volvo Intestinal/cirurgia , Masculino
7.
J Pediatr Surg ; 57(11): 710-715, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-35197196

RESUMO

BACKGROUND: The omental flap has numerous extraperitoneal applications in reconstruction and revascularization given its favorable immunologic and angiogenic properties. In patients with Moyamoya disease, cerebral revascularization using a pedicled omental flap has proven to be a viable option following direct revascularization procedures. Historically, harvesting omentum involved laparotomy with the associated risk of complications; herein we describe outcomes from a 10-year experience of laparoscopic harvesting of pedicled omental flap for cerebral revascularization in Moyamoya patients. METHODS: A retrospective chart review was performed of all patients with Moyamoya disease who underwent laparoscopic omental cerebral transposition between 2011 and 2021. Intraoperative and postoperative complications, length of stay (LOS), and outcomes at follow-up were analyzed. RESULTS: Twenty-one patients underwent the procedure during the study period. Three intraoperative complications occurred (one segmental transverse colectomy for mesenteric injury, one converted to omental free flap, and one requiring micro anastomosis). Average overall LOS was 6 ± 6 days, with 3 ± 3.5 days in the ICU (mean±SD). Following discharge, complications included epigastric incisional hernia at the graft fascial exit site, recurrent neck pain at subcutaneous tunneling site, and partial scalp necrosis. One patient required subsequent direct bypass seven months after the initial procedure owing to the progression of the disease. All other patients had partial or complete resolution of symptoms. CONCLUSION: Our retrospective observational study indicates that laparoscopic pedicled omental flap mobilization and transposition is a safe and effective method of indirect cerebral revascularization in patients with Moyamoya disease. LEVEL OF EVIDENCE: N/A.


Assuntos
Revascularização Cerebral , Laparoscopia , Doença de Moyamoya , Revascularização Cerebral/métodos , Humanos , Laparoscopia/métodos , Doença de Moyamoya/cirurgia , Omento/cirurgia , Estudos Retrospectivos , Retalhos Cirúrgicos/transplante
8.
Pediatr Surg Int ; 27(7): 689-93, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21293866

RESUMO

INTRODUCTION: Seasonal variation in the incidence of hypertrophic pyloric stenosis (HPS) has been long debated. The goal of this study was to determine if seasonal variation exists in the incidence of pyloric stenosis. METHODS: A population-based cohort consisted of all infants in the province of Ontario, Canada with HPS from 1993 to 2000. The incidence of HPS per season was adjusted by birth rate and expressed as number of pyloromyotomies per 100,000 infants less than 12 months of age. One-way analysis of variance was used to compare HPS incidence between seasons. Further time series and spectral analysis were performed to examine for seasonal variation. RESULTS: There were 1,777 infants included in the population-based cohort. June was the month with the highest rate of HPS. The highest rate of pyloromyotomy occurred in the summer 14.92 and the lowest in the winter 10.73, this difference was statistically significant (p = 0.01). Spectral analysis showed that June was the month with the highest rate and February had the lowest rates p = 0.0014. CONCLUSION: Hypertrophic pyloric stenosis more commonly presents in the summer. Seasonal variation suggests a possible etiological role for environmental factors.


Assuntos
Vigilância da População/métodos , Estenose Pilórica Hipertrófica/epidemiologia , Estações do Ano , Procedimentos Cirúrgicos do Sistema Digestório/métodos , Feminino , Seguimentos , Humanos , Incidência , Lactente , Masculino , Ontário/epidemiologia , Prognóstico , Estenose Pilórica Hipertrófica/cirurgia , Piloro/cirurgia , Estudos Retrospectivos , Fatores de Risco
9.
AJR Am J Roentgenol ; 192(5): 1269-71, 2009 May.
Artigo em Inglês | MEDLINE | ID: mdl-19380551

RESUMO

OBJECTIVE: The purpose of this study was to describe the clinical, imaging, and surgical findings in the cases of four neonates with radiographic findings suggesting duodenal atresia (double-bubble sign) who were subsequently found to have malrotation with midgut volvulus. CONCLUSION: When the surgical treatment of a patient with the double-bubble sign is to be delayed, an upper gastrointestinal radiographic or ultrasound study is needed to evaluate for malrotation with midgut volvulus.


Assuntos
Duodenopatias/diagnóstico por imagem , Volvo Intestinal/diagnóstico por imagem , Diagnóstico Diferencial , Duodenopatias/cirurgia , Feminino , Humanos , Recém-Nascido , Volvo Intestinal/cirurgia , Masculino , Radiografia
10.
Surg Endosc ; 23(1): 103-7, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18528614

RESUMO

BACKGROUND: Inguinal hernia in children is traditionally repaired through a groin incision by dissecting the hernia sac from the spermatic cord and suture ligating its base. A laparoscopic modification of this procedure involves placement of a transcutaneous suture around the neck of the sac through a 2-mm stab incision under visualization with an umbilically placed 2.7-mm 30 degrees lens. We reviewed the clinical outcome of this novel procedure at our institution. METHODS: Prospective review of 275 hernias in 187 children (144 male, 43 female) performed laparoscopically by a single surgeon between September, 2002 and June, 2005. Data analyzed included side of hernia, incarceration, prematurity, recurrence rate, and complications. RESULTS: 30 left, 69 right, and 25 bilateral hernias were repaired. Sixty-three unilateral hernias had a contralateral patent processus vaginalis that was repaired. Mean operative time for a bilateral repair was 17 min. Two procedures were for recurrence after open repair. Forty-nine patients were ex-premature infants, accounting for 79 repairs. Fifteen cases followed reduction of incarcerated hernias, nine of whom were in preterm infants. Four out of 275 hernias (1.5%) recurred in four patients (mean age 4.5 years; 3 male, 1 female). There were four superficial wound infections, two umbilical granulomas, two hydroceles, and six self-resolving hematomas. There were no spermatic cord injuries, testicular atrophy, or symptoms of ilioinguinal nerve injuries. CONCLUSION: This novel laparoscopic inguinal hernia repair is an effective method in children, with recurrence rates comparable to the traditional approach. Advantages of the laparoscopic operation include a "no-touch" approach to the spermatic cord structures, a virtually virgin operative field in cases of recurrence, and excellent cosmesis. Disadvantages include peritoneal access and nonhermetic seal in males.


Assuntos
Hérnia Inguinal/cirurgia , Laparoscopia , Suturas , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Lactente , Masculino , Recidiva , Estudos Retrospectivos , Técnicas de Sutura , Fatores de Tempo , Resultado do Tratamento
11.
Transplantation ; 85(9): 1287-9, 2008 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-18475185

RESUMO

BACKGROUND: Very young pediatric patients awaiting intestinal transplantation have a high mortality rate due to long waiting times, scarcity of appropriate size donor organs, and mortality due to sepsis and liver failure. To investigate specific risk factors impacting survival to intestinal transplantation, we performed a 4-year institutional retrospective study comparing children who received grafts by age 18 months with children 18 months or younger who died while on the waiting list. PATIENTS AND METHODS: Twelve children comprised the transplanted group and had the underlying diagnoses: necrotizing enterocolitis, gastroschisis, Hirschsprung's disease, and omphalocele. Ten children comprised the deceased group and had the underlying diagnoses: intestinal atresia, necrotizing enterocolitis, gastroschisis, and midgut volvulus. Multiple risk factors were assessed in these groups. RESULTS: No differences in residual small bowel length, presence of the colon, number of line infections, or number of central lines were found. The average body weight of the transplanted group trended higher, whereas the deceased group had more impairment of hepatic function. Intestinal atresia was the most common diagnosis in the deceased group while none of the transplanted group carried this diagnosis. Ileocecal valve was retained in 80% of the deceased group and in none of the transplanted group. CONCLUSIONS: In children younger than 18 months, risk factors affecting survival to intestinal transplantation include small body size and advanced liver disease. A primary diagnosis of intestinal atresia and the presence of the ileocecal valve may confer additional risk to these very young children.


Assuntos
Intestinos/transplante , Peso Corporal , Humanos , Lactente , Enteropatias/classificação , Enteropatias/cirurgia , Testes de Função Hepática , Complicações Pós-Operatórias/classificação , Complicações Pós-Operatórias/epidemiologia , Análise de Sobrevida , Sobreviventes , Fatores de Tempo , Listas de Espera
12.
Mol Imaging Biol ; 10(1): 19-23, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-17975716

RESUMO

Intraoperative gamma probe guidance has become widely utilized for sentinel lymph node dissection in patients with breast cancer and melanoma, using (99m)Tc sulfur colloid. However, new indications are possible and need to continue to be investigated. We report the use during a wedge liver biopsy of a new hand-held gamma probe designed for (123)I intraoperative guidance. The patient studied is a 5-year-old boy with history of stage 4 high-risk neuroblastoma. Anatomic imaging (CT, MRI), (99m)Tc bone scintigraphy and 2-deoxy-2-[F-18]fluoro-d-glucose-positron emission tomography/computed tomography (FDG-PET/CT) were negative, but the (123)I MIBG scintigraphy suggested recurrent liver disease. A decision was made to biopsy these lesions to obtain histopathological confirmation. Intraoperative gamma probe mapping of the liver identified areas with signal above the background, but these were prove to be hemosiderin deposits on histo-pathology examination.


Assuntos
3-Iodobenzilguanidina , Cuidados Intraoperatórios , Neoplasias Hepáticas/diagnóstico , Recidiva Local de Neoplasia/diagnóstico , Neuroblastoma/diagnóstico , Pré-Escolar , Fluordesoxiglucose F18 , Humanos , Radioisótopos do Iodo , Masculino , Tomografia por Emissão de Pósitrons , Tomografia Computadorizada de Emissão de Fóton Único
13.
Obes Surg ; 18(3): 332-5, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18193180

RESUMO

In this case report, we present an 18-year-old morbidly obese male with complicating hypertensive cardiomyopathy who underwent laparoscopic adjustable gastric band surgery. The patient had multiple comorbidities associated with his obesity, including obstructive sleep apnea, systemic hypertension, asthma, and depression. Given the severity of his underlying cardiac pathology and multiple previously unsuccessful attempts at weight loss with conventional medical and behavioral therapy, the patient opted to proceed with surgical intervention. We present this laparoscopic adjustable gastric banding surgical case to demonstrate the impact of surgical weight reduction on cardiac risk factors in a morbidly obese adolescent, highlighting the viability of this surgery for patients with existing cardiac dysfunction.


Assuntos
Cardiomiopatia Hipertrófica/complicações , Gastroplastia , Laparoscopia , Obesidade Mórbida/cirurgia , Adolescente , Humanos , Masculino , Obesidade Mórbida/complicações
14.
Surg Endosc ; 22(7): 1643-8, 2008 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-18027029

RESUMO

BACKGROUND: Coil occlusion (CO) and video-assisted thoracoscopic surgery (VATS) have both emerged as minimal access therapies for patent ductus arteriosus (PDA). These techniques have not previously been statistically compared. METHODS: Twenty-four consecutive children undergoing VATS for PDA were each retrospectively matched by PDA diameter and child weight to two children undergoing CO (total 48) during the same time period. The two modalities were compared with respect to outcome and cost. Statistical analysis was performed using a Student's t-test and Mantel-Haenszel relative risk. Cost analysis from an institutional perspective was used to compare resource consumption. RESULTS: Mean PDA diameter was 3.6 +/- 1.2 mm in both groups. Mean age and weight for VATS and CO children were 2.7 and 2.9 yrs and 13.2 and 13.1 kg, respectively. Mean surgical times were 94 +/- 34 min for VATS and 50 +/- 23 min for CO (p < 0.0001). Mean length of stay was 1.6 +/- 0.2 days for VATS and 0.6 +/- 0.2 days for CO (Mantel-Haenszel RR (95% CI) = 0.15 [0.07, 0.29], p < 0.0001). Mean fluoroscopy time with CO was 13 +/- 7 min. No VATS or CO children required conversion to open surgical ligation. Two children in each arm (8% VATS, 4% CO) required indefinite antibiotic endarteritis prophylaxis for a persistent shunt. The cost per child was C$ 4282.80 (Canadian dollars) for VATS and C$ 3958.08 for CO. CONCLUSIONS: VATS is as efficacious for PDA closure as CO but requires longer surgical times and lengths of stay. Costs for each procedure are similar.


Assuntos
Oclusão com Balão/economia , Permeabilidade do Canal Arterial/terapia , Doenças do Prematuro/terapia , Ligadura/métodos , Cirurgia Torácica Vídeoassistida/economia , Pré-Escolar , Estudos de Coortes , Custos e Análise de Custo , Permeabilidade do Canal Arterial/diagnóstico por imagem , Permeabilidade do Canal Arterial/economia , Ecocardiografia , Feminino , Humanos , Recém-Nascido , Doenças do Prematuro/diagnóstico por imagem , Doenças do Prematuro/economia , Tempo de Internação/economia , Masculino , Estudos Retrospectivos , Toracotomia , Resultado do Tratamento
15.
Surg Neurol ; 70(5): 492-5; discussion 495-7, 2008 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18207538

RESUMO

BACKGROUND: Patients with ventriculoperitoneal shunts (VPSs) inserted for a variety of disorders may subsequently undergo gastrointestinal or urologic operations, and surgeons must determine the appropriate perioperative management to minimize the risk for shunt malfunction or infection. There is currently no established set of guidelines for this scenario. The objective of this study was to determine the risks and standard of practice for patients with VPSs undergoing abdominal surgery. METHODS: A retrospective review of the charts of patients with VPSs who underwent abdominal or urologic surgery at the Stanford University Medical Center between 1995 and 2003 was performed. Data regarding type of abdominal surgery, level of contamination, choice of antibiotic therapy, perioperative management of the VPS, and outcomes were obtained. RESULTS: Twenty-six patient charts were reviewed, for a total of 39 operations (5 urologic, 23 upper gastrointestinal, and 11 lower gastrointestinal). Of these, 3 were clean, 34 were clean-contaminated, and 2 were dirty operations. Seven cases were laparoscopic, whereas 32 were open. Thirty-four cases required opening the bowel or urologic system. No patient had preoperative shunt externalization. All except one patient received pre- and postoperative antibiotics, but the duration and type of antibiotics were widely variable. The remaining patient had an inguinal hernia repair and received only one preoperative dose of cephalexin. Purulent fluid was found in 2 cases. One VPS found lying in purulent material next to an anastomotic leak was externalized and subsequently revised. However, in another patient, a VPS found lying next to a purulent jejunal tear was not externalized. This patient returned 2 months later with a VPS malfunction. In the remaining 35 cases, no VPS infection or malfunction was noted over 2 to 10 years of follow-up. CONCLUSIONS: The data suggest that there is minimal risk for VPS malfunction or infection among patients undergoing routine clean and clean-contaminated abdominal and urologic surgeries. Patients with VPSs undergoing these operations do not need externalization of their shunt. None of the patients in this study had a contaminated procedure. For dirty procedures, surgeons should opt to externalize the shunt. Future studies will aim to better standardize the perioperative management of VPSs during abdominal surgery.


Assuntos
Antibioticoprofilaxia , Procedimentos Cirúrgicos do Sistema Digestório , Assistência Perioperatória , Infecções Relacionadas à Prótese/prevenção & controle , Procedimentos Cirúrgicos Urológicos , Derivação Ventriculoperitoneal , Abdome/cirurgia , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Estudos de Coortes , Falha de Equipamento , Feminino , Humanos , Hidrocefalia/cirurgia , Laparoscopia , Masculino , Pessoa de Meia-Idade , Infecções Relacionadas à Prótese/etiologia , Reoperação , Estudos Retrospectivos , Derivação Ventriculoperitoneal/efeitos adversos , Derivação Ventriculoperitoneal/instrumentação
16.
Comput Aided Surg ; 13(2): 63-81, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18317956

RESUMO

One of the most important advantages of computer simulators for surgical training is the opportunity they afford for independent learning. However, if the simulator does not provide useful instructional feedback to the user, this advantage is significantly blunted by the need for an instructor to supervise and tutor the trainee while using the simulator. Thus, the incorporation of relevant, intuitive metrics is essential to the development of efficient simulators. Equally as important is the presentation of such metrics to the user in such a way so as to provide constructive feedback that facilitates independent learning and improvement. This paper presents a number of novel metrics for the automated evaluation of surgical technique. The general approach was to take criteria that are intuitive to surgeons and develop ways to quantify them in a simulator. Although many of the concepts behind these metrics have wide application throughout surgery, they have been implemented specifically in the context of a simulation of mastoidectomy. First, the visuohaptic simulator itself is described, followed by the details of a wide variety of metrics designed to assess the user's performance. We present mechanisms for presenting visualizations and other feedback based on these metrics during a virtual procedure. We further describe a novel performance evaluation console that displays metric-based information during an automated debriefing session. Finally, the results of several user studies are reported, providing some preliminary validation of the simulator, the metrics, and the feedback mechanisms. Several machine learning algorithms, including Hidden Markov Models and a Naïve Bayes Classifier, are applied to our simulator data to automatically differentiate users' expertise levels.


Assuntos
Competência Clínica , Simulação por Computador , Instrução por Computador/métodos , Retroalimentação , Internato e Residência , Processo Mastoide/cirurgia , Computação Matemática , Otolaringologia/educação , Cirurgia Assistida por Computador/educação , Interface Usuário-Computador , Algoritmos , Competência Clínica/normas , Avaliação Educacional/normas , Humanos , Reprodutibilidade dos Testes , Software
17.
J Laparoendosc Adv Surg Tech A ; 28(5): 617-621, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29446701

RESUMO

PURPOSE: Benign masses of the eyebrow and forehead are common in pediatric patients and can result in facial asymmetry, discomfort, or super-infection. Excision is classically conducted via an incision directly over the mass, which can produce sub-optimal cosmesis. Recently, an endoscopic approach using pediatric brow-lift equipment has been adopted. We reviewed our center's experience with endoscopic removal of benign facial lesions and compared these cases with an equivalent series of open cases. MATERIALS AND METHODS: A retrospective chart review was conducted to identify pediatric cases of endoscopic and open removal of benign eyebrow or forehead lesions at our institution from 2009 to 2016. Clinical and cosmetic outcomes were reviewed. RESULTS: A total of 40 endoscopic and 25 open cases of excision of benign facial lesions in children were identified. For the patients who underwent endoscopic excision, the majority (85%) presented with a cyst located at the eyebrow. Histologic examination revealed 36 dermoid cysts (90%), 2 epidermal cysts, and 2 pilomatrixomas. Of the 36 cases with post-operative follow-up, 32 patients (89%) had an uncomplicated recovery with good cosmesis. Two patients had an eyebrow droop that resolved without intervention. One patient had localized numbness overlying the site, but no motor deficits. One patient presented with a recurrent dermoid cyst that required open resection. For the patients who underwent open excision, the majority (52%) had dermoid cysts located at the eyebrow. Of the 22 cases with follow-up, 20 of the patients had an uncomplicated recovery (90%). Comparing the rate of complications, there was no statistically significant difference between the two groups (P = 1.0). CONCLUSION: Endoscopic excision of benign forehead and eyebrow lesions in pediatric patients is feasible and yields excellent cosmetic results. When compared with open excision, complication rates are similar between both approaches and a facial scar can be avoided with an endoscopic approach.


Assuntos
Cisto Dermoide/cirurgia , Endoscopia/métodos , Neoplasias Faciais/cirurgia , Doenças do Cabelo/cirurgia , Pilomatrixoma/cirurgia , Neoplasias Cutâneas/cirurgia , Adolescente , Criança , Pré-Escolar , Cicatriz/etiologia , Endoscopia/efeitos adversos , Cisto Epidérmico/cirurgia , Sobrancelhas , Feminino , Testa , Humanos , Lactente , Recém-Nascido , Masculino , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Resultado do Tratamento
19.
J Laparoendosc Adv Surg Tech A ; 17(2): 258-64, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17484663

RESUMO

PURPOSE: Minimal access portoenterostomy (Kasai procedure) for biliary atresia represents a technically challenging operation. The standard laparoscopic approach yields results comparable to the open technique. After an initial experience with standard laparoscopy, we assessed the potentially superior optics and dexterity of a surgical robotic system for performing portoenterostomy. We reviewed our experience with minimal access portoenterostomy to compare the relative advantages and disadvantages of standard laparoscopic and robotic approaches to biliary atresia. MATERIALS AND METHODS: We reviewed the charts of all patients who underwent either laparoscopic or robotic portoenterostomy at our institution between October 2002 and October 2005. Outcome measures included the need to convert to laparotomy, complications, functional outcome expressed either as the direct bilirubin at most recent follow-up (> or = 3 months) or age at transplant, and density of adhesions at transplant. Surgeons' impressions of the two minimal access modalities were also reviewed. RESULTS: A total of 10 patients underwent minimal access portoenterostomy (7 standard laparoscopy; 3 robotic-assisted). Mean follow-up was 20 months (range, 1-36 months). There were no conversions to laparotomy and no intraoperative complications. There was one port site infection that resolved with antibiotics. Five patients (4 laparoscopic, 1 robotic) had progressed to transplantation at the time of follow-up. At transplant, one patient had mild adhesions and two had dense adhesions. Adhesions were not noted for 2 patients. CONCLUSION: We believe both surgical modalities are feasible from a technical point of view. However, the optical and dexterity advantages of the robotic system were offset by the large instrument size and lack of force feedback.


Assuntos
Atresia Biliar/cirurgia , Laparoscopia/métodos , Portoenterostomia Hepática/métodos , Robótica/métodos , Anastomose em-Y de Roux/métodos , Humanos , Lactente , Estudos Retrospectivos
20.
J Laparoendosc Adv Surg Tech A ; 17(3): 391-4, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17570796

RESUMO

BACKGROUND: Morgagni hernias are well suited to laparoscopic repair. A primary suture closure may result in tension on the repair, thereby predisposing the patient to a recurrence. A prosthetic patch (PP) can be used to provide a tension-free repair. In this study, we reviewed our experience with the laparoscopic PP repair of Morgagni hernias in children. METHODS: A retrospective chart review of all patients undergoing a laparoscopic Morgagni hernia repair using a PP was undertaken between November 2002 and January 2006. Outcome measures included age, gender, defect size, use of mesh, and outcome. The time of follow-up was from 6 to 37 months. RESULTS: Seven (7) patients (6 male, 1 female) underwent a laparoscopic repair of Morgagni hernia during this time period. Six (6) patients had a congenital hernia, and 1 patient was thought to have an iatrogenic hernia following a sternotomy for heart surgery. Defect size ranged from 4 to 7 cm in maximum dimension. All operations were completed laparoscopically, no patients presented with recurrence, and no PP complications were encountered. CONCLUSIONS: The laparoscopic repair of Morgagni hernia using a PP can be performed with relative ease and with a positive outcome, and may prevent future recurrence by effecting a tension-free repair.


Assuntos
Materiais Biocompatíveis , Hérnia Diafragmática/cirurgia , Laparoscopia/métodos , Politetrafluoretileno , Próteses e Implantes , Fatores Etários , Criança , Pré-Escolar , Feminino , Seguimentos , Hérnia Diafragmática/classificação , Hérnias Diafragmáticas Congênitas , Humanos , Lactente , Masculino , Recidiva , Estudos Retrospectivos , Fatores Sexuais , Telas Cirúrgicas , Resultado do Tratamento
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