Detalhe da pesquisa
1.
Activity and safety of enobosarm, a novel, oral, selective androgen receptor modulator, in androgen receptor-positive, oestrogen receptor-positive, and HER2-negative advanced breast cancer (Study G200802): a randomised, open-label, multicentre, multinational, parallel design, phase 2 trial.
Lancet Oncol
; 25(3): 317-325, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38342115
2.
Arming androgen receptors to oppose oncogenic estrogen receptor activity in breast cancer.
Br J Cancer
; 125(12): 1599-1601, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34294894
3.
Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer.
Br J Cancer
; 124(1): 217-227, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33144693
4.
Glucocorticoid receptors are required effectors of TGFß1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer.
Breast Cancer Res
; 22(1): 39, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32357907
5.
Reticulon-1 and Reduced Migration toward Chemoattractants by Macrophages Differentiated from the Bone Marrow of Ultraviolet-Irradiated and Ultraviolet-Chimeric Mice.
J Immunol
; 200(1): 260-270, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29167231
6.
Selective inhibition of CDK9 in triple negative breast cancer.
Oncogene
; 43(3): 202-215, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38001268
7.
The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.
Genome Biol
; 25(1): 44, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38317241
8.
Glucocorticoid Receptors Drive Breast Cancer Cell Migration and Metabolic Reprogramming via PDK4.
Endocrinology
; 164(7)2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37224504
9.
Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity.
EMBO Mol Med
; 15(12): e17737, 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37902007
10.
Breast Tumor Kinase (Brk/PTK6) Mediates Advanced Cancer Phenotypes via SH2-Domain Dependent Activation of RhoA and Aryl Hydrocarbon Receptor (AhR) Signaling.
Mol Cancer Res
; 19(2): 329-345, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33172975
11.
High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids.
SLAS Discov
; 26(9): 1107-1124, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34111999
12.
90 YEARS OF PROGESTERONE: Steroid receptors as MAPK signaling sensors in breast cancer: let the fates decide.
J Mol Endocrinol
; 65(1): T35-T48, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32209723
13.
Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice.
Cancer Immunol Res
; 8(4): 428-435, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31992566
14.
Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates.
Endocrinology
; 160(2): 430-446, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30597041
15.
Promotion of Tumor Invasion by Tumor-Associated Macrophages: The Role of CSF-1-Activated Phosphatidylinositol 3 Kinase and Src Family Kinase Motility Signaling.
Cancers (Basel)
; 9(6)2017 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28629162
16.
PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo.
Exp Hematol
; 56: 64-68, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28822771
17.
A three-dimensional co-culture system to investigate macrophage-dependent tumor cell invasion.
J Biol Methods
; 3(3): e49, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-31453214
18.
Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration.
J Leukoc Biol
; 100(1): 163-75, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26747837