Detalhe da pesquisa
1.
Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo.
Proc Natl Acad Sci U S A
; 110(45): 18244-9, 2013 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24145449
2.
Functional imaging of legumain in cancer using a new quenched activity-based probe.
J Am Chem Soc
; 135(1): 174-82, 2013 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23215039
3.
Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model.
Arthritis Rheum
; 64(4): 1098-109, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22006294
4.
Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin.
Oncotarget
; 6(13): 11175-90, 2015 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25883214
5.
The apoptosis repressor with a CARD domain (ARC) gene is a direct hypoxia-inducible factor 1 target gene and promotes survival and proliferation of VHL-deficient renal cancer cells.
Mol Cell Biol
; 34(4): 739-51, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24344197
6.
In vivo imaging and biochemical characterization of protease function using fluorescent activity-based probes.
Curr Protoc Chem Biol
; 5(1): 25-44, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23788323
7.
An optimized activity-based probe for the study of caspase-6 activation.
Chem Biol
; 19(3): 340-52, 2012 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22444589
8.
A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages.
Chem Biol
; 19(5): 619-28, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22633413
9.
Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity.
Chem Biol
; 19(12): 1535-45, 2012 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142757
10.
Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes.
Curr Opin Chem Biol
; 15(6): 798-805, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22098719
11.
Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe.
PLoS One
; 6(11): e28029, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22132198
12.
Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity.
PLoS One
; 4(7): e6374, 2009 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19636372
13.
Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes.
Nat Med
; 15(8): 967-73, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19597506