Detalhe da pesquisa
1.
Functionalized triazines as potent HCV entry inhibitors.
Bioorg Med Chem Lett
; 27(4): 1089-1093, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28089701
2.
Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068.
J Antimicrob Chemother
; 69(3): 573-81, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24128669
3.
Inhibitors of HIV-1 attachment. Part 11: the discovery and structure-activity relationships associated with 4,6-diazaindole cores.
Bioorg Med Chem Lett
; 23(1): 218-22, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23206859
4.
Inhibitors of HIV-1 attachment. Part 9: an assessment of oral prodrug approaches to improve the plasma exposure of a tetrazole-containing derivative.
Bioorg Med Chem Lett
; 23(1): 209-12, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23200244
5.
Inhibitors of HIV-1 attachment. Part 7: indole-7-carboxamides as potent and orally bioavailable antiviral agents.
Bioorg Med Chem Lett
; 23(1): 198-202, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23200252
6.
In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068.
Antimicrob Agents Chemother
; 56(7): 3498-507, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22547625
7.
A novel small molecule inhibitor of hepatitis C virus entry.
PLoS Pathog
; 6(9): e1001086, 2010 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20838466
8.
In vivo patterns of resistance to the HIV attachment inhibitor BMS-488043.
Antimicrob Agents Chemother
; 55(2): 729-37, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21078948
9.
Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-naïve patients is rare through 5 years of therapy.
Hepatology
; 49(5): 1503-14, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19280622
10.
Comprehensive evaluation of hepatitis B virus reverse transcriptase substitutions associated with entecavir resistance.
Hepatology
; 47(5): 1473-82, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18435459
11.
Impairment of type I but not type III IFN signaling by hepatitis C virus infection influences antiviral responses in primary human hepatocytes.
PLoS One
; 10(3): e0121734, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25826356
12.
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1h-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248).
J Med Chem
; 56(4): 1656-69, 2013 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23360431
13.
High-throughput screening and rapid inhibitor triage using an infectious chimeric Hepatitis C virus.
PLoS One
; 7(8): e42609, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22880053
14.
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 5. An evolution from indole to azaindoles leading to the discovery of 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a drug candidate that demonstrates antiviral activity in HIV-1-infected subjects.
J Med Chem
; 52(23): 7778-87, 2009 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19769332
15.
Hepatitis B virus quasispecies susceptibility to entecavir confirms the relationship between genotypic resistance and patient virologic response.
J Hepatol
; 48(6): 895-902, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18362040
16.
Inhibition of hepatitis B virus polymerase by entecavir.
J Virol
; 81(8): 3992-4001, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17267485
17.
Two-year assessment of entecavir resistance in Lamivudine-refractory hepatitis B virus patients reveals different clinical outcomes depending on the resistance substitutions present.
Antimicrob Agents Chemother
; 51(3): 902-11, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17178796
18.
Entecavir resistance is rare in nucleoside naïve patients with hepatitis B.
Hepatology
; 44(6): 1656-65, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17133475
19.
parC mutations in fluoroquinolone-resistant Borrelia burgdorferi.
Antimicrob Agents Chemother
; 49(10): 4354-7, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16189120