Pesquisa | Biblioteca Virtual em Saúde

1.

Inefficient CAR-proximal signaling blunts antigen sensitivity.

Gudipati, Venugopal; Rydzek, Julian; Doel-Perez, Iago; Gonçalves, Vasco Dos Reis; Scharf, Lydia; Königsberger, Sebastian; Lobner, Elisabeth; Kunert, Renate; Einsele, Hermann; Stockinger, Hannes; Hudecek, Michael; Huppa, Johannes B.

Nat Immunol ; 21(8): 848-856, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32632291

2.

BATF3 programs CD8⁺ T cell memory.

Ataide, Marco A; Komander, Karl; Knöpper, Konrad; Peters, Annika E; Wu, Hao; Eickhoff, Sarah; Gogishvili, Tea; Weber, Justus; Grafen, Anika; Kallies, Axel; Garbi, Natalio; Einsele, Hermann; Hudecek, Michael; Gasteiger, Georg; Hölzel, Michael; Vaeth, Martin; Kastenmüller, Wolfgang.

Nat Immunol ; 21(11): 1397-1407, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32989328

3.

Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.

Sonneveld, Pieter; Dimopoulos, Meletios A; Boccadoro, Mario; Quach, Hang; Ho, P Joy; Beksac, Meral; Hulin, Cyrille; Antonioli, Elisabetta; Leleu, Xavier; Mangiacavalli, Silvia; Perrot, Aurore; Cavo, Michele; Belotti, Angelo; Broijl, Annemiek; Gay, Francesca; Mina, Roberto; Nijhof, Inger S; van de Donk, Niels W C J; Katodritou, Eirini; Schjesvold, Fredrik; Sureda Balari, Anna; Rosiñol, Laura; Delforge, Michel; Roeloffzen, Wilfried; Silzle, Tobias; Vangsted, Annette; Einsele, Hermann; Spencer, Andrew; Hajek, Roman; Jurczyszyn, Artur; Lonergan, Sarah; Ahmadi, Tahamtan; Liu, Yanfang; Wang, Jianping; Vieyra, Diego; van Brummelen, Emilie M J; Vanquickelberghe, Veronique; Sitthi-Amorn, Anna; de Boer, Carla J; Carson, Robin; Rodriguez-Otero, Paula; Bladé, Joan; Moreau, Philippe.

N Engl J Med ; 390(4): 301-313, 2024 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-38084760

4.

Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma.

San-Miguel, Jesús; Dhakal, Binod; Yong, Kwee; Spencer, Andrew; Anguille, Sébastien; Mateos, María-Victoria; Fernández de Larrea, Carlos; Martínez-López, Joaquín; Moreau, Philippe; Touzeau, Cyrille; Leleu, Xavier; Avivi, Irit; Cavo, Michele; Ishida, Tadao; Kim, Seok Jin; Roeloffzen, Wilfried; van de Donk, Niels W C J; Dytfeld, Dominik; Sidana, Surbhi; Costa, Luciano J; Oriol, Albert; Popat, Rakesh; Khan, Abdullah M; Cohen, Yaël C; Ho, P Joy; Griffin, James; Lendvai, Nikoletta; Lonardi, Carolina; Slaughter, Ana; Schecter, Jordan M; Jackson, Carolyn C; Connors, Kaitlyn; Li, Katherine; Zudaire, Enrique; Chen, Diana; Gilbert, Jane; Yeh, Tzu-Min; Nagle, Sarah; Florendo, Erika; Pacaud, Lida; Patel, Nitin; Harrison, Simon J; Einsele, Hermann.

N Engl J Med ; 389(4): 335-347, 2023 Jul 27.

Artigo em Inglês | MEDLINE | ID: mdl-37272512

5.

CAR T-cell therapy in multiple myeloma: mission accomplished?

Rasche, Leo; Hudecek, Michael; Einsele, Hermann.

Blood ; 143(4): 305-310, 2024 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-38033289

6.

Sequential antigen loss and branching evolution in lymphoma after CD19- and CD20-targeted T-cell-redirecting therapy.

Duell, Johannes; Leipold, Alexander M; Appenzeller, Silke; Fuhr, Viktoria; Rauert-Wunderlich, Hilka; Da Via, Matteo; Dietrich, Oliver; Toussaint, Christophe; Imdahl, Fabian; Eisele, Florian; Afrin, Nazia; Grundheber, Lars; Einsele, Hermann; Weinhold, Niels; Rosenwald, Andreas; Topp, Max S; Saliba, Antoine-Emmanuel; Rasche, Leo.

Blood ; 143(8): 685-696, 2024 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-37976456

7.

International Myeloma Working Group immunotherapy committee consensus guidelines and recommendations for optimal use of T-cell-engaging bispecific antibodies in multiple myeloma.

Rodriguez-Otero, Paula; Usmani, Saad; Cohen, Adam D; van de Donk, Niels W C J; Leleu, Xavier; Pérez-Larraya, Jaime Gállego; Manier, Salomon; Nooka, Ajay K; Mateos, Maria Victoria; Einsele, Hermann; Minnema, Monique; Cavo, Michele; Derman, Benjamin A; Puig, Noemi; Gay, Francesca; Ho, P Joy; Chng, Wee-Joo; Kastritis, Efstathios; Gahrton, Gösta; Weisel, Katja; Nagarajan, Chandramouli; Schjesvold, Fredik; Mikhael, Joseph; Costa, Luciano; Raje, Noopur S; Zamagni, Elena; Hájek, Roman; Weinhold, Niels; Yong, Kwee; Ye, Jing Christine; Sidhana, Surbhi; Merlini, Giampaolo; Martin, Tom; Lin, Yi; Chari, Ajai; Popat, Rakesh; Kaufman, Jonathan L.

Lancet Oncol ; 25(5): e205-e216, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38697166

8.

Changes in T-cell subsets, preexisting cytopenias and hyperferritinaemia correlate with cytopenias after BCMA targeted CAR T-cell therapy in relapsed/refractory multiple myeloma: Results from a prospective comprehensive biomarker study.

Zhou, Xiang; Wagner, Vivien; Scheller, Lukas; Stanojkovska, Emilia; Riedhammer, Christine; Xiao, Xianghui; Steinhardt, Maximilian Johannes; Vogt, Cornelia; Nerreter, Silvia; Eisele, Florian; John, Mara; Munawar, Umair; Kadel, Sofie-Katrin; Mersi, Julia; Ruckdeschel, Anna; Schimanski, Sven; Haertle, Larissa; Waldschmidt, Johannes Moritz; Han, Seungbin; Topp, Max; Duell, Johannes; Einsele, Hermann; Riedel, Angela; Kortüm, K Martin; Rasche, Leo.

Br J Haematol ; 2024 May 08.

Artigo em Inglês | MEDLINE | ID: mdl-38719214

9.

Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma.

Munshi, Nikhil C; Anderson, Larry D; Shah, Nina; Madduri, Deepu; Berdeja, Jesús; Lonial, Sagar; Raje, Noopur; Lin, Yi; Siegel, David; Oriol, Albert; Moreau, Philippe; Yakoub-Agha, Ibrahim; Delforge, Michel; Cavo, Michele; Einsele, Hermann; Goldschmidt, Hartmut; Weisel, Katja; Rambaldi, Alessandro; Reece, Donna; Petrocca, Fabio; Massaro, Monica; Connarn, Jamie N; Kaiser, Shari; Patel, Payal; Huang, Liping; Campbell, Timothy B; Hege, Kristen; San-Miguel, Jesús.

N Engl J Med ; 384(8): 705-716, 2021 02 25.

Artigo em Inglês | MEDLINE | ID: mdl-33626253

10.

CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome.

Taube, Franziska; Georgi, Julia Annabell; Kramer, Michael; Stasik, Sebastian; Middeke, Jan Moritz; Röllig, Christoph; Krug, Utz; Krämer, Alwin; Scholl, Sebastian; Hochhaus, Andreas; Brümmendorf, Tim H; Naumann, Ralph; Petzold, Andreas; Mulet-Lazaro, Roger; Valk, Peter J M; Steffen, Björn; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Schäfer-Eckart, Kerstin; Schliemann, Christoph; Krause, Stefan W; Hänel, Mathias; Noppeney, Richard; Kaiser, Ulrich; Baldus, Claudia D; Kaufmann, Martin; Herold, Sylvia; Stölzel, Friedrich; Sockel, Katja; von Bonin, Malte; Müller-Tidow, Carsten; Platzbecker, Uwe; Berdel, Wolfgang E; Serve, Hubert; Ehninger, Gerhard; Bornhäuser, Martin; Schetelig, Johannes; Thiede, Christian.

Blood ; 139(1): 87-103, 2022 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-34320176

11.

Allogeneic hematopoietic stem cell transplantation in patients aged 60-79 years in Germany (1998-2018): a registry study.

Weller, Jan Frederic; Lengerke, Claudia; Finke, Jürgen; Schetelig, Johannes; Platzbecker, Uwe; Einsele, Hermann; Schroeder, Thomas; Faul, Christoph; Stelljes, Matthias; Dreger, Peter; Blau, Igor W; Wulf, Gerald; Tischer, Johanna; Scheid, Christoph; Elmaagacli, Ahmet; Neidlinger, Helga; Flossdorf, Sarah; Bornhäuser, Martin; Bethge, Wolfgang; Fleischhauer, Katharina; Kröger, Nicolaus; De Wreede, Liesbeth C; Christopeit, Maximilian.

Haematologica ; 109(2): 431-443, 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-37646665

12.

Soluble B-cell maturation antigen in lacrimal fluid as a potential biomarker and mediator of keratopathy in multiple myeloma.

Munawar, Umair; Theuersbacher, Johanna; Steinhardt, Maximilian J; Zhou, Xiang; Han, Seungbin; Nerreter, Silvia; Vogt, Cornelia; Kurian, Shilpa; Keller, Thorsten; Regensburger, Ann-Katrin; Teufel, Eva; Mersi, Julia; Bittrich, Max; Seifert, Franziska; Haider, Malik S; Rasche, Leo; Hillenkamp, Jost; Einsele, Hermann; Kampik, Daniel; Kortüm, K Martin; Waldschmidt, Johannes M.

Haematologica ; 2024 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-38572568

13.

Time from diagnosis to treatment has no impact on survival in newly diagnosed acute myeloid leukemia treated with venetoclax-based regimens.

Baden, David; Zukunft, Sven; Hernandez, Gema; Wolgast, Nadine; Steinhauser, Sophie; Pohlmann, Alexander; Schliemann, Christoph; Mikesch, Jan-Henrik; Steffen, Bjorn; Sauer, Tim; Hanoun, Maher; Schafer-Eckart, Kerstin; Krause, Stefan W; Hanel, Mathias; Einsele, Hermann; Jost, Edgar; Brummendorf, Tim H; Scholl, Sebastian; Hochhaus, Andreas; Neubauer, Andreas; Burchert, Andreas; Kaufmann, Martin; Niemann, Dirk; Schaich, Markus; Blau, Wolfgang; Kiani, Alexander; Gorner, Martin; Kaiser, Ulrich; Kullmer, Johannes; Weber, Thomas; Berdel, Wolfgang E; Ehninger, Gerhard; Muller-Tidow, Carsten; Platzbecker, Uwe; Serve, Hubert; Bornhauser, Martin; Rollig, Christoph; Baldus, Claudia D; Fransecky, Lars.

Haematologica ; 2024 Apr 24.

Artigo em Inglês | MEDLINE | ID: mdl-38654660

14.

Chemokine receptor-targeted PET/CT provides superior diagnostic performance in newly diagnosed marginal zone lymphoma patients: a head-to-head comparison with [¹⁸F]FDG.

Kosmala, Aleksander; Duell, Johannes; Schneid, Simone; Serfling, Sebastian E; Higuchi, Takahiro; Weich, Alexander; Lapa, Constantin; Hartrampf, Philipp E; Raderer, Markus; Einsele, Hermann; Buck, Andreas K; Topp, Max S; Schlötelburg, Wiebke; Werner, Rudolf A.

Eur J Nucl Med Mol Imaging ; 51(3): 749-755, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37943339

15.

Prevention and management of adverse events during treatment with bispecific antibodies and CAR T cells in multiple myeloma: a consensus report of the European Myeloma Network.

Ludwig, Heinz; Terpos, Evangelos; van de Donk, Niels; Mateos, Maria-Victoria; Moreau, Philippe; Dimopoulos, Melitios-Athanasios; Delforge, Michel; Rodriguez-Otero, Paula; San-Miguel, Jesús; Yong, Kwee; Gay, Francesca; Einsele, Hermann; Mina, Roberto; Caers, Jo; Driessen, Christoph; Musto, Pellegrino; Zweegman, Sonja; Engelhardt, Monika; Cook, Gordon; Weisel, Katja; Broijl, Annemiek; Beksac, Meral; Bila, Jelena; Schjesvold, Fredrik; Cavo, Michele; Hajek, Roman; Touzeau, Cyrille; Boccadoro, Mario; Sonneveld, Pieter.

Lancet Oncol ; 24(6): e255-e269, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37269857

16.

Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia.

Jetani, Hardikkumar; Navarro-Bailón, Almudena; Maucher, Marius; Frenz, Silke; Verbruggen, Christina; Yeguas, Ana; Vidriales, María Belén; González, Marcos; Rial Saborido, Judit; Kraus, Sabrina; Mestermann, Katrin; Thomas, Simone; Bonig, Halvard; Luu, Maik; Monjezi, Razieh; Mougiakakos, Dimitrios; Sauer, Markus; Einsele, Hermann; Hudecek, Michael.

Blood ; 138(19): 1830-1842, 2021 11 11.

Artigo em Inglês | MEDLINE | ID: mdl-34289026

17.

Cereblon enhancer methylation and IMiD resistance in multiple myeloma.

Haertle, Larissa; Barrio, Santiago; Munawar, Umair; Han, Seungbin; Zhou, Xiang; Vogt, Cornelia; Fernández, Rafael Alonso; Bittrich, Max; Ruiz-Heredia, Yanira; Da Viá, Matteo; Zovko, Josip; Garitano-Trojaola, Andoni; Bolli, Niccolò; Ruckdeschel, Anna; Stühmer, Thorsten; Chatterjee, Manik; Kull, Miriam; Krönke, Jan; Agirre, Xabier; Martin-Subero, Jose I; Raab, Peter; Einsele, Hermann; Rasche, Leo; Martinez-Lopez, Joaquin; Haaf, Thomas; Kortüm, K Martin.

Blood ; 138(18): 1721-1726, 2021 11 04.

Artigo em Inglês | MEDLINE | ID: mdl-34115836

18.

BCMA loss in the epoch of novel immunotherapy for multiple myeloma: from biology to clinical practice.

Zhou, Xiang; Rasche, Leo; Kortüm, K Martin; Mersi, Julia; Einsele, Hermann.

Haematologica ; 108(4): 958-968, 2023 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-36263838

19.

Adjusted comparison of outcomes between patients from CARTITUDE-1 versus multiple myeloma patients with prior exposure to proteasome inhibitors, immunomodulatory drugs and anti-CD38 antibody from the prospective, multinational LocoMMotion study of real-world clinical practice.

Mateos, Maria-Victoria; Weisel, Katja; Martin, Thomas; Berdeja, Jesús G; Jakubowiak, Andrzej; Stewart, A Keith; Jagannath, Sundar; Lin, Yi; Diels, Joris; Ghilotti, Francesca; Thilakarathne, Pushpike; Perualila, Nolen J; Cabrieto, Jedelyn; Haefliger, Benjamin; Erler-Yates, Nichola; Hague, Clare; Jackson, Carolyn C; Schecter, Jordan M; Strulev, Vadim; Nesheiwat, Tonia; Pacaud, Lida; Einsele, Hermann; Moreau, Philippe.

Haematologica ; 108(8): 2192-2204, 2023 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-36546453

20.

High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the ß2 and ß1 subunits of the proteasome complex.

Zhou, Xiang; Besse, Andrej; Peter, Jessica; Steinhardt, Maximilian Johannes; Vogt, Cornelia; Nerreter, Silvia; Teufel, Eva; Stanojkovska, Emilia; Xiao, Xianghui; Hornburger, Hannah; Haertle, Larissa; Lopez, Max Mendez; Munawar, Umair; Riedel, Angela; Han, Seungbin; Maurits, Elmer; Overkleeft, Herman S; Florea, Bogdan; Einsele, Hermann; Kortüm, K Martin; Driessen, Christoph; Besse, Lenka; Rasche, Leo.

Haematologica ; 108(6): 1628-1639, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-36727403

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