Detalhe da pesquisa
1.
A non-canonical tricarboxylic acid cycle underlies cellular identity.
Nature
; 603(7901): 477-481, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35264789
2.
Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.
Mol Cell
; 78(6): 1096-1113.e8, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32416067
3.
Age-induced accumulation of methylmalonic acid promotes tumour progression.
Nature
; 585(7824): 283-287, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814897
4.
Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.
JCI Insight
; 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38815134
5.
Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.
bioRxiv
; 2023 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37546939
6.
Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells.
Sci Adv
; 8(20): eabm8786, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594343
7.
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.
Nat Commun
; 13(1): 6239, 2022 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36266345
8.
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.
Cancer Cell
; 40(9): 939-956.e16, 2022 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35985343
9.
Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics.
Sci Signal
; 14(686)2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34103421
10.
Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia.
iScience
; 24(6): 102651, 2021 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34151238
11.
Targeting oncoproteins with a positive selection assay for protein degraders.
Sci Adv
; 7(6)2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33547076
12.
Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.
Cell Metab
; 29(5): 1166-1181.e6, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30799286