Detalhe da pesquisa
1.
Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK.
Mol Cell
; 81(18): 3803-3819.e7, 2021 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547240
2.
Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs.
Nucleic Acids Res
; 49(4): 2065-2084, 2021 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33555350
3.
Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M1dG, the Genomic Metabolite of M1dG, and Liquid Chromatography-Tandem Mass Spectrometry Analysis of Its In Vitro Bypass by Human Polymerase ι.
Chem Res Toxicol
; 34(12): 2567-2578, 2021 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34860508
4.
LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation.
Nucleic Acids Res
; 47(12): 6236-6249, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30982887
5.
Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion.
Int J Mol Sci
; 22(19)2021 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34639060
6.
A Facile Semisynthesis and Evaluation of Garcinoic Acid and Its Analogs for the Inhibition of Human DNA Polymerase ß.
Molecules
; 25(24)2020 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33322249
7.
A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells.
Biochemistry
; 57(7): 1262-1273, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29345908
8.
A catch and release program for single-stranded DNA.
J Biol Chem
; 292(31): 13085-13086, 2017 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28778884
9.
Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase Are Involved in Unwinding G-quadruplex DNA.
J Biol Chem
; 292(8): 3154-3163, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28069813
10.
Evidence That G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress.
J Biol Chem
; 291(34): 18041-57, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27369081
11.
Translesion DNA Synthesis in Cancer: Molecular Mechanisms and Therapeutic Opportunities.
Chem Res Toxicol
; 30(11): 1942-1955, 2017 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28841374
12.
Human Translesion Polymerase κ Exhibits Enhanced Activity and Reduced Fidelity Two Nucleotides from G-Quadruplex DNA.
Biochemistry
; 55(37): 5218-29, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27525498
13.
Aberrant Kynurenine Signaling Modulates DNA Replication Stress Factors and Promotes Genomic Instability in Gliomas.
Chem Res Toxicol
; 29(9): 1369-80, 2016 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27482758
14.
Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex Bypass Activities of Human DNA Polymerase REV1.
Chem Res Toxicol
; 29(3): 367-79, 2016 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26914252
15.
Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells.
Chem Res Toxicol
; 29(1): 101-8, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26651356
16.
Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors.
Pharmacol Res
; 113(Pt A): 335-347, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27637375
17.
Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells.
Bioorg Med Chem Lett
; 26(9): 2164-9, 2016 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27017113
18.
The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa.
Nucleic Acids Res
; 42(19): 12027-40, 2014 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25294835
19.
Human Rev1 polymerase disrupts G-quadruplex DNA.
Nucleic Acids Res
; 42(5): 3272-85, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366879
20.
Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes.
Proc Natl Acad Sci U S A
; 110(27): E2470-9, 2013 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23754438