Detalhe da pesquisa
1.
Comparable Pharmacokinetics, Safety, and Tolerability of Etrolizumab Administered by Prefilled Syringe or Autoinjector in a Randomized Trial in Healthy Volunteers.
Adv Ther
; 38(5): 2418-2434, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33778929
2.
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease.
Sci Transl Med
; 13(593)2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33980574
3.
Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma.
J Pathol
; 218(3): 380-90, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19334050
4.
Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL-22Fc): A Potential Therapy for Epithelial Injury.
Clin Pharmacol Ther
; 105(1): 177-189, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29952004
5.
Cellular Mechanisms of Etrolizumab Treatment in Inflammatory Bowel Disease.
Front Pharmacol
; 10: 39, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30774593
6.
Measurement of IL-17AA and IL-17FF as Pharmacodynamic Biomarkers to Demonstrate Target Engagement in the Phase I Study of MCAF5352A.
AAPS J
; 21(1): 9, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30547287
7.
Pharmacokinetic and Pharmacodynamic Modeling of Serum Etrolizumab and Circulating ß7 Receptor Occupancy in Patients With Ulcerative Colitis.
J Clin Pharmacol
; 58(3): 386-398, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29178491
8.
Overcoming disease-specific matrix effect in a clinical pharmacokinetic assay using a microfluidic immunoassay technology.
Bioanalysis
; 9(16): 1207-1216, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28766364
9.
Critical role of bioanalytical strategies in investigation of clinical PK observations, a Phase I case study.
MAbs
; 6(6): 1500-8, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25484037
10.
Utilizing design of experiments to characterize assay robustness.
Bioanalysis
; 4(17): 2127-39, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23013395