Detalhe da pesquisa
1.
LPS Triggers Acute Neuroinflammation and Parkinsonism Involving NLRP3 Inflammasome Pathway and Mitochondrial CI Dysfunction in the Rat.
Int J Mol Sci
; 24(5)2023 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36902058
2.
Regulation of human GDNF gene expression in nigral dopaminergic neurons using a new doxycycline-regulated NTS-polyplex nanoparticle system.
Nanomedicine
; 13(4): 1363-1375, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28219741
3.
Neurotensin-polyplex-mediated brain-derived neurotrophic factor gene delivery into nigral dopamine neurons prevents nigrostriatal degeneration in a rat model of early Parkinson's disease.
J Biomed Sci
; 22: 59, 2015 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26198255
4.
Focused ultrasound on the substantia nigra enables safe neurotensin-polyplex nanoparticle-mediated gene delivery to dopaminergic neurons intranasally and by blood circulation.
Discov Nano
; 19(1): 60, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38564106
5.
Unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neuropathology and behavioral deficits in parkinsonian rats with α-synucleinopathy.
Neural Regen Res
; 19(9): 2057-2067, 2024 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38227536
6.
Cerebral dopamine neurotrophic factor transfection in dopamine neurons using neurotensin-polyplex nanoparticles reverses 6-hydroxydopamine-induced nigrostriatal neurodegeneration.
Neural Regen Res
; 17(4): 854-866, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-34472486
7.
Intranigral Administration of ß-Sitosterol-ß-D-Glucoside Elicits Neurotoxic A1 Astrocyte Reactivity and Chronic Neuroinflammation in the Rat Substantia Nigra.
J Immunol Res
; 2020: 5907591, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33282962
8.
Development of a Parenteral Formulation of NTS-Polyplex Nanoparticles for Clinical Purpose.
Pharmaceutics
; 10(1)2018 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301386
9.
Neurturin overexpression in dopaminergic neurons induces presynaptic and postsynaptic structural changes in rats with chronic 6-hydroxydopamine lesion.
PLoS One
; 12(11): e0188239, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29176874
10.
The transfection of BDNF to dopamine neurons potentiates the effect of dopamine D3 receptor agonist recovering the striatal innervation, dendritic spines and motor behavior in an aged rat model of Parkinson's disease.
PLoS One
; 10(2): e0117391, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25693197