Detalhe da pesquisa
1.
Antitumor alkyl ether lipid edelfosine: tissue distribution and pharmacokinetic behavior in healthy and tumor-bearing immunosuppressed mice.
Clin Cancer Res
; 15(3): 858-64, 2009 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19188156
2.
Nanomedicine and drug delivery systems in cancer and regenerative medicine.
Wiley Interdiscip Rev Nanomed Nanobiotechnol
; 12(5): e1637, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32351045
3.
Trimethylamine-N-Oxide (TMAO) Predicts Cardiovascular Mortality in Peripheral Artery Disease.
Sci Rep
; 9(1): 15580, 2019 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31666590
4.
Discovery of in Vivo Chemical Probes for Treating Alzheimer's Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors.
ACS Chem Neurosci
; 10(3): 1765-1782, 2019 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525452
5.
Multitarget Approach for the Treatment of Alzheimer's Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles.
ACS Chem Neurosci
; 10(9): 4076-4101, 2019 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31441641
6.
Lipid nanoparticles for alkyl lysophospholipid edelfosine encapsulation: development and in vitro characterization.
Eur J Pharm Biopharm
; 68(2): 207-13, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17707618
7.
Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease.
Eur J Med Chem
; 150: 506-524, 2018 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29549837
8.
GPR55: A therapeutic target for Parkinson's disease?
Neuropharmacology
; 125: 319-332, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28807673
9.
Gastroresistant oral peptide for fluorescence imaging of colonic inflammation.
J Control Release
; 262: 118-126, 2017 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28734901
10.
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies.
Nat Commun
; 8: 15424, 2017 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28548080
11.
Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer's Disease.
J Med Chem
; 59(19): 8967-9004, 2016 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27606546
12.
Diagnostic and therapeutic uses of nanomaterials in the brain.
Curr Med Chem
; 21(36): 4100-31, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25139519
13.
Efficacy of edelfosine lipid nanoparticles in breast cancer cells.
Int J Pharm
; 454(2): 720-6, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23643510
14.
Edelfosine lipid nanosystems overcome drug resistance in leukemic cell lines.
Cancer Lett
; 334(2): 302-10, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23353057
15.
Lipid nanoparticles for cancer therapy: state of the art and future prospects.
Expert Opin Drug Deliv
; 9(10): 1245-61, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22950878
16.
Complete inhibition of extranodal dissemination of lymphoma by edelfosine-loaded lipid nanoparticles.
Nanomedicine (Lond)
; 7(5): 679-90, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22630151
17.
In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma.
J Control Release
; 156(3): 421-6, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21821074
18.
In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts.
Clin Cancer Res
; 16(7): 2046-54, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20233887
19.
Lipid nanomedicines for anticancer drug therapy.
J Biomed Nanotechnol
; 5(4): 323-43, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20055079