Detalhe da pesquisa
1.
APC and P53 mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer.
Gut
; 72(12): 2294-2306, 2023 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591698
2.
Biochemical analysis of DNA synthesis blockage by G-quadruplex structure and bypass facilitated by a G4-resolving helicase.
Methods
; 204: 207-214, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34929333
3.
Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro.
Hum Mol Genet
; 29(8): 1292-1309, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32191790
4.
RecQ and Fe-S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions.
Biochem Soc Trans
; 46(1): 77-95, 2018 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29273621
5.
Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere damage repair.
J Mol Cell Biol
; 2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37771090
6.
Impacts of radiation exposure, hindlimb unloading, and recovery on murine skeletal muscle cell telomere length.
NPJ Microgravity
; 9(1): 76, 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37714858
7.
GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells.
Elife
; 112022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35559731
8.
G4-Interacting DNA Helicases and Polymerases: Potential Therapeutic Targets.
Curr Med Chem
; 26(16): 2881-2897, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-29149833