Detalhe da pesquisa
1.
A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression.
Cell
; 184(3): 675-688.e19, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33421369
2.
PlyKp104, a Novel Phage Lysin for the Treatment of Klebsiella pneumoniae, Pseudomonas aeruginosa, and Other Gram-Negative ESKAPE Pathogens.
Antimicrob Agents Chemother
; 67(5): e0151922, 2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37098944
3.
Strains of bacterial species induce a greatly varied acute adaptive immune response: The contribution of the accessory genome.
PLoS Pathog
; 14(1): e1006726, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29324905
4.
Isolation of Phage Lysins That Effectively Kill Pseudomonas aeruginosa in Mouse Models of Lung and Skin Infection.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010858
5.
Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962344
6.
Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii.
Antimicrob Agents Chemother
; 60(5): 2671-9, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26856847
7.
Using a Novel Lysin To Help Control Clostridium difficile Infections.
Antimicrob Agents Chemother
; 59(12): 7447-57, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26392484
8.
Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia model.
Antimicrob Agents Chemother
; 59(4): 1983-91, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605353
9.
A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae.
J Antimicrob Chemother
; 70(6): 1763-73, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733585
10.
A highly active and negatively charged Streptococcus pyogenes lysin with a rare D-alanyl-L-alanine endopeptidase activity protects mice against streptococcal bacteremia.
Antimicrob Agents Chemother
; 58(6): 3073-84, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24637688
11.
Anti-CRISPR proteins trigger a burst of CRISPR-Cas9 expression that enhances phage defense.
Cell Rep
; 43(3): 113849, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427560
12.
Novel bacteriophage lysin with broad lytic activity protects against mixed infection by Streptococcus pyogenes and methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother
; 57(6): 2743-50, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23571534
13.
PaP1, a Broad-Spectrum Lysin-Derived Cationic Peptide to Treat Polymicrobial Skin Infections.
Front Microbiol
; 13: 817228, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35369520
14.
Prophage integration into CRISPR loci enables evasion of antiviral immunity in Streptococcus pyogenes.
Nat Microbiol
; 6(12): 1516-1525, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34819640
15.
Gram-Negative Bacterial Lysins.
Antibiotics (Basel)
; 9(2)2020 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32054067
16.
Evaluation of Topical Lysostaphin as a Novel Treatment for Instrumented Rhesus Macaques (Macaca mulatta) Infected with Methicillin-Resistant Staphylococcus aureus.
Comp Med
; 70(5): 335-347, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32792040
17.
Staphylococcus aureus Infecting and Colonizing Experimental Animals, Macaques, in a Research Animal Facility.
Microb Drug Resist
; 25(1): 54-62, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30481118
18.
Novel algorithms reveal streptococcal transcriptomes and clues about undefined genes.
PLoS Comput Biol
; 3(7): e132, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17616984
19.
Watch your Strep: Streptococcus pyogenes is a preventable cause of maternal death.
Future Microbiol
; 17: 319-323, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35114817
20.
The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa.
PLoS One
; 12(1): e0169180, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28046082