RESUMO
A total of 65 women in labor complicated with uterine inertia were investigated for tissue pO2 and cardiac performance of fetuses under the effect of oxytocin. The authors stated that the aggravation of fetal status in drug-induced labors resulted from poorer tissue oxygenation caused by the activation of uterine contractility. In this line, hypoxic changes of the fetus were more pronounced in pregnancies complicated by nephropathy or prolonged pregnancy. Accurate monitoring of the fetal status and the character of induced labor course was found to be mandatory. Before oxytocin induction the fetus should be protected with diazepam.
Assuntos
Coração Fetal/efeitos dos fármacos , Feto/efeitos dos fármacos , Trabalho de Parto Induzido , Consumo de Oxigênio/efeitos dos fármacos , Ocitocina/farmacologia , Adulto , Feminino , Coração Fetal/fisiologia , Hipóxia Fetal/induzido quimicamente , Hipóxia Fetal/prevenção & controle , Monitorização Fetal , Feto/fisiologia , Humanos , Consumo de Oxigênio/fisiologia , Ocitocina/toxicidade , GravidezRESUMO
The data on the formation of blastocysts in culture during therapeutic cycles of extracorporeal fertilization and on cytotoxic index of the endometrium in women with different clinical pathogenetic variants of sterility are presented. Analysis of correlations of these parameters with the incidence of effective implantation and pregnancy revealed a strict correlation between cytotoxic activity of endometrial immunocompetent cells and human embryo implantation.