Detalhe da pesquisa
1.
Stability and sub-cellular localization of DNA polymerase ß is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.
Nucleic Acids Res
; 47(12): 6269-6286, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31287140
2.
Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase ß in vivo.
Proc Natl Acad Sci U S A
; 112(28): 8602-7, 2015 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26124145
3.
The Versatile Attributes of MGMT: Its Repair Mechanism, Crosstalk with Other DNA Repair Pathways, and Its Role in Cancer.
Cancers (Basel)
; 16(2)2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38254819
4.
TRIP12 governs DNA Polymerase ß involvement in DNA damage response and repair.
bioRxiv
; 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645048
5.
DNA-protein crosslinks processed by nucleotide excision repair and homologous recombination with base and strand preference in E. coli model system.
Mutat Res
; 741-742: 1-10, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23500083
6.
Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases.
J Biol Chem
; 285(11): 8185-95, 2010 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20026607
7.
Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis.
Cell Rep
; 37(5): 109917, 2021 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34731617
8.
Cytosine methylation effects on the repair of O6-methylguanines within CG dinucleotides.
J Biol Chem
; 284(34): 22601-10, 2009 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19531487
9.
Synthesis and characterization of an O(6)-2'-deoxyguanosine-alkyl-O(6)-2'-deoxyguanosine interstrand cross-link in a 5'-GNC motif and repair by human O(6)-alkylguanine-DNA alkyltransferase.
Org Biomol Chem
; 8(19): 4414-26, 2010 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20714665
10.
Structural basis for putrescine activation of human S-adenosylmethionine decarboxylase.
Biochemistry
; 47(50): 13404-17, 2008 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19053272
11.
Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase.
Biochemistry
; 47(41): 10892-903, 2008 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18803403
12.
Human variants of O6-alkylguanine-DNA alkyltransferase.
DNA Repair (Amst)
; 6(8): 1071-8, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17482892
13.
Differential inactivation of polymorphic variants of human O6-alkylguanine-DNA alkyltransferase.
Biochem Pharmacol
; 75(3): 618-26, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17996846
14.
DNA sequence context affects repair of the tobacco-specific adduct O(6)-[4-Oxo-4-(3-pyridyl)butyl]guanine by human O(6)-alkylguanine-DNA alkyltransferases.
Cancer Res
; 66(9): 4968-74, 2006 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16651455
15.
Inactivation of O(6)-alkylguanine-DNA alkyltransferase by folate esters of O(6)-benzyl-2'-deoxyguanosine and of O(6)-[4-(hydroxymethyl)benzyl]guanine.
J Med Chem
; 50(21): 5193-201, 2007 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17880193
16.
Etheno-DNA adduct formation in rats gavaged with linoleic acid, oleic acid and coconut oil is organ- and gender specific.
Mutat Res
; 624(1-2): 71-9, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17521682
17.
Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations.
Mol Cancer Ther
; 3(9): 1127-35, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15367707
18.
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase ß.
Nat Commun
; 5: 5513, 2014 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25423885
19.
The base excision repair pathway is required for efficient lentivirus integration.
PLoS One
; 6(3): e17862, 2011 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21448280
20.
Substitution of aminomethyl at the meta-position enhances the inactivation of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine.
J Med Chem
; 51(22): 7144-53, 2008 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18973327