Detalhe da pesquisa
1.
The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.
Cell
; 185(12): 2035-2056.e33, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35688132
2.
Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model.
Genome Res
; 34(4): 590-605, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38599684
3.
Pathways controlling neurotoxicity and proteostasis in mitochondrial complex I deficiency.
Hum Mol Genet
; 33(10): 860-871, 2024 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38324746
4.
α-Synuclein Promotes Neuronal Dysfunction and Death by Disrupting the Binding of Ankyrin to ß-Spectrin.
J Neurosci
; 43(9): 1614-1626, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36653193
5.
α-synuclein impairs autophagosome maturation through abnormal actin stabilization.
PLoS Genet
; 17(2): e1009359, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33556113
6.
Anastasis Drives Senescence and Non-Cell Autonomous Neurodegeneration in the Astrogliopathy Alexander Disease.
J Neurosci
; 42(12): 2584-2597, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35105675
7.
Nicotine-Mediated Rescue of α-Synuclein Toxicity Requires Synaptic Vesicle Glycoprotein 2 in Drosophila.
Mov Disord
; 38(2): 244-255, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36416213
8.
Toward More Accessible Fully Automated 3D Volumetric MRI Decision Trees for the Differential Diagnosis of Multiple System Atrophy, Related Disorders, and Age-Matched Healthy Subjects.
Cerebellum
; 22(6): 1098-1108, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36156185
9.
Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model.
Proc Natl Acad Sci U S A
; 117(52): 33608-33618, 2020 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318181
10.
Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping.
Cerebellum
; 2022 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36190676
11.
Parkinson's disease risk genes act in glia to control neuronal α-synuclein toxicity.
Neurobiol Dis
; 159: 105482, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390834
12.
Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics.
PLoS Biol
; 16(12): e2006265, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30571694
13.
A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo.
J Neurosci
; 38(1): 108-119, 2018 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29138281
14.
Glial α-synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo.
Glia
; 67(10): 1933-1957, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31267577
15.
Case Study 4: A 68-Year-Old Woman With Progressive Cognitive Decline and Anxiety.
J Neuropsychiatry Clin Neurosci
; 35(1): 4-11, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36633473
16.
Case Study 6: The Diagnostic Challenge of a 75-Year-Old Man Who Had, Then Didn't Have, Then Did Have Alzheimer's Disease.
J Neuropsychiatry Clin Neurosci
; 35(4): 325-332, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37840261
17.
An In Vivo Pharmacological Screen Identifies Cholinergic Signaling as a Therapeutic Target in Glial-Based Nervous System Disease.
J Neurosci
; 36(5): 1445-55, 2016 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26843629
18.
Defective Phagocytic Corpse Processing Results in Neurodegeneration and Can Be Rescued by TORC1 Activation.
J Neurosci
; 36(11): 3170-83, 2016 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26985028
19.
Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form.
Neurobiol Dis
; 106: 191-204, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28711409
20.
PARP Inhibitors and Parkinson's Disease.
N Engl J Med
; 380(5): 492-494, 2019 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30699325