Detalhe da pesquisa
1.
Novel potent (dihydro)benzofuranyl piperazines as human histamine receptor ligands - Functional characterization and modeling studies on H3 and H4 receptors.
Bioorg Med Chem
; 30: 115924, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33333448
2.
The Novel H4R Antagonist 1-[(5-Chloro-2,3-Dihydro-1-Benzofuran-2-Yl)Methyl]-4-Methyl-Piperazine (LINS01007) Attenuates Several Symptoms in Murine Allergic Asthma.
Cell Physiol Biochem
; 54(6): 1163-1176, 2020 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33216475
3.
The histamine H4 receptor antagonist 1-[(5-chloro-2,3-dihydro-1-benzofuran-2-yl)methyl]-4-methyl-piperazine(LINS01007) prevents the development of DSS-induced colitis in mice.
Int Immunopharmacol
; 133: 112128, 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38652966
4.
Evaluation of the histamine H3 receptor antagonists from LINS01 series as cholinesterases inhibitors: Enzymatic and modeling studies.
Chem Biol Drug Des
; 100(5): 722-729, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36050829
5.
Novel potent vasodilating agents: Evaluation of the activity and potency of LINS01005 and derivatives in rat aorta.
Eur J Pharm Sci
; 143: 105171, 2020 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31805391