Detalhe da pesquisa
1.
Variant-specific effects of GBA1 mutations on dopaminergic neuron proteostasis.
J Neurochem
; 2024 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38641924
2.
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.
Hum Mol Genet
; 28(12): 2001-2013, 2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753527
3.
Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.
Nucleic Acids Res
; 44(22): 10960-10973, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27536002
4.
Changes in Oxidised Phospholipids in Response to Oxidative Stress in Microtubule-Associated Protein Tau (MAPT) Mutant Dopamine Neurons.
Antioxidants (Basel)
; 13(5)2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38790613
5.
Beyond the lysosome: Cholesterol role on endoplasmic reticulum and lipid droplets in Parkinson's disease.
Mov Disord
; 33(2): 342, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29205489
6.
Mitochondrial and Endoplasmic Reticulum Stress Trigger Triglyceride Accumulation in Models of Parkinson's Disease Independent of Mutations in MAPT.
Metabolites
; 13(1)2023 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36677037
7.
CRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death.
Sci Rep
; 13(1): 3934, 2023 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36894612
8.
Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson's disease GBA-N370S dopamine neurons.
Cell Rep
; 42(3): 112180, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870058
9.
Cellular reprogramming: a new approach to modelling Parkinson's disease.
Biochem Soc Trans
; 40(5): 1152-7, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22988881
10.
MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development.
Genome Biol
; 22(1): 43, 2021 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33482885
11.
Development and Application of High-Throughput Single Cell Lipid Profiling: A Study of SNCA-A53T Human Dopamine Neurons.
iScience
; 23(11): 101703, 2020 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33196026
12.
Single-Cell Transcriptomics of Parkinson's Disease Human In Vitro Models Reveals Dopamine Neuron-Specific Stress Responses.
Cell Rep
; 33(2): 108263, 2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33053338
13.
Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.
Nat Commun
; 10(1): 1817, 2019 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31000720
14.
Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.
Nat Commun
; 10(1): 2530, 2019 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31164655
15.
ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.
Stem Cell Reports
; 6(3): 342-56, 2016 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26905200
16.
Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models.
Front Neurosci
; 10: 578, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28066164