Detalhe da pesquisa
1.
Genome-wide characterization of circulating metabolic biomarkers.
Nature
; 628(8006): 130-138, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38448586
2.
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Am J Hum Genet
; 110(2): 284-299, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36693378
3.
Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.
Am J Hum Genet
; 109(10): 1727-1741, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055244
4.
Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood.
Diabetologia
; 66(8): 1472-1480, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37280435
5.
Statins and risk of type 2 diabetes: mechanism and clinical implications.
Front Endocrinol (Lausanne)
; 14: 1239335, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37795366
6.
Plasma Metabolite Signatures in Male Carriers of Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease.
Metabolites
; 13(2)2023 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36837886
7.
Metabolites as Risk Factors for Diabetic Retinopathy in Patients With Type 2 Diabetes: A 12-Year Follow-up Study.
J Clin Endocrinol Metab
; 109(1): 100-106, 2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37560996
8.
Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits.
Diabetes
; 72(11): 1707-1718, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37647564
9.
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake.
Nat Genet
; 55(6): 973-983, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37291194
10.
Genetics of Type 2 Diabetes: Past, Present, and Future.
Nutrients
; 14(15)2022 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35956377
11.
Metabolite Signature of Simvastatin Treatment Involves Multiple Metabolic Pathways.
Metabolites
; 12(8)2022 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005625
12.
Effects of SLCO1B1 Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment.
Metabolites
; 12(12)2022 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36557197
13.
Metabolite Signature of Physical Activity and the Risk of Type 2 Diabetes in 7271 Men.
Metabolites
; 12(1)2022 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35050191
14.
Metabolite Signature in the Carriers of Pathogenic Genetic Variants for Cardiomyopathy: A Population-Based METSIM Study.
Metabolites
; 12(5)2022 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35629941
15.
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.
Nat Commun
; 13(1): 1644, 2022 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35347128
16.
The "Common Soil Hypothesis" Revisited-Risk Factors for Type 2 Diabetes and Cardiovascular Disease.
Metabolites
; 11(10)2021 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34677406
17.
Metabolite Signature of Albuminuria Involves Amino Acid Pathways in 8661 Finnish Men Without Diabetes.
J Clin Endocrinol Metab
; 106(1): 143-152, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32992327
18.
The Obesity Risk SNP (rs17782313) near the MC4R Gene Is Not Associated with Brain Glucose Uptake during Insulin Clamp-A Study in Finns.
J Clin Med
; 10(6)2021 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33806715
19.
Microbiota-Related Metabolites and the Risk of Type 2 Diabetes.
Diabetes Care
; 43(6): 1319-1325, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32295805
20.
An intronic variant in the GCKR gene is associated with multiple lipids.
Sci Rep
; 9(1): 10240, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31308433