Detalhe da pesquisa
1.
Continuous Flow Acylation of (Hetero)aryllithiums with Polyfunctional N,N-Dimethylamides and Tetramethylurea in Toluene.
Chemistry
; 27(56): 13977-13981, 2021 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387898
2.
Application of Transition-Metal Catalysis, Biocatalysis, and Flow Chemistry as State-of-the-Art Technologies in the Synthesis of LCZ696.
J Org Chem
; 85(11): 6844-6853, 2020 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32412751
3.
Fouling of Flow Reactors in Organolithium Mediated Transformations: Experience on Scale-up and Proposed Solution.
Chimia (Aarau)
; 73(10): 809-816, 2019 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31645241
4.
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy.
Biochim Biophys Acta
; 1844(10): 1765-72, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25062913
5.
Glucuronidation of bile acids under flow conditions: design of experiments and Koenigs-Knorr reaction optimization.
Org Biomol Chem
; 12(47): 9592-600, 2014 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25338931
6.
Synthesis and quantitative structure-property relationships of side chain-modified hyodeoxycholic acid derivatives.
Molecules
; 18(9): 10497-513, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23999724
7.
Extending SAR of bile acids as FXR ligands: discovery of 23-N-(carbocinnamyloxy)-3α,7α-dihydroxy-6α-ethyl-24-nor-5ß-cholan-23-amine.
Bioorg Med Chem
; 19(8): 2650-8, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21459580
8.
Regioselective difunctionalization of pyridines via 3,4-pyridynes.
Chem Sci
; 12(17): 6143-6147, 2021 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33996011
9.
Intramuscular neridronate in postmenopausal women with low bone mineral density.
Calcif Tissue Int
; 83(5): 301-7, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18946626
10.
Discovery of 3α,7α,11ß-Trihydroxy-6α-ethyl-5ß-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders.
J Med Chem
; 59(19): 9201-9214, 2016 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27652492
11.
Effects of S 21403 on hormone secretion from isolated rat pancreas at different glucose concentrations.
Eur J Pharmacol
; 456(1-3): 141-7, 2002 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12450580
12.
Building a sulfonamide library by eco-friendly flow synthesis.
ACS Comb Sci
; 15(5): 235-9, 2013 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23514257
13.
Bone mineral density in haemophilia patients. A meta-analysis.
Thromb Haemost
; 103(3): 596-603, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20076854
14.
Injectable bisphosphonates in the treatment of postmenopausal osteoporosis.
Aging Clin Exp Res
; 15(4): 271-83, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-14661816
15.
The effect of age, weight, and lifestyle factors on calcaneal quantitative ultrasound: the ESOPO study.
Osteoporos Int
; 14(3): 198-207, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12730794
16.
Effects of high dose methylprednisolone pulse therapy on bone mass and biochemical markers of bone metabolism in patients with active rheumatoid arthritis: a 12-month randomized prospective controlled study.
J Rheumatol
; 31(6): 1083-7, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15170918