Detalhe da pesquisa
1.
Epsin2, a novel target for multiple system atrophy therapy via α-synuclein/FABP7 propagation.
Brain
; 146(8): 3172-3180, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37082980
2.
Pharmacological inhibition of FABP7 by MF 6 counteracts cerebellum dysfunction in an experimental multiple system atrophy mouse model.
Acta Pharmacol Sin
; 45(1): 66-75, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37605049
3.
Understanding the potential causes of gastrointestinal dysfunctions in multiple system atrophy.
Neurobiol Dis
; 187: 106296, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37714308
4.
Tailored behavioural tests reveal early and progressive cognitive deficits in M1000 prion disease.
Neurobiol Dis
; 180: 106075, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914075
5.
Pathogenic Impact of α-Synuclein Phosphorylation and Its Kinases in α-Synucleinopathies.
Int J Mol Sci
; 23(11)2022 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35682892
6.
Fibrillar α-synuclein toxicity depends on functional lysosomes.
J Biol Chem
; 295(51): 17497-17513, 2020 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33453994
7.
Therapeutic potential of iron modulating drugs in a mouse model of multiple system atrophy.
Neurobiol Dis
; 159: 105509, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34537326
8.
PrPSc Oligomerization Appears Dynamic, Quickly Engendering Inherent M1000 Acute Synaptotoxicity.
Biophys J
; 119(1): 128-141, 2020 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32562618
9.
The role of lipids in α-synuclein misfolding and neurotoxicity.
J Biol Chem
; 294(23): 9016-9028, 2019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31064841
10.
Therapeutic applications of chelating drugs in iron metabolic disorders of the brain and retina.
J Neurosci Res
; 98(10): 1889-1904, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32643793
11.
Exercise and physical activity for people with Progressive Supranuclear Palsy: a systematic review.
Clin Rehabil
; 34(1): 23-33, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31559853
12.
l-3,4-dihydroxyphenylalanine (l-DOPA) modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha-synuclein mouse models of Parkinson's disease.
J Neurochem
; 150(1): 88-106, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30716176
13.
N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease.
Hum Mol Genet
; 25(14): 2923-2933, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27179791
14.
Parkinson's disease iron deposition caused by nitric oxide-induced loss of ß-amyloid precursor protein.
J Neurosci
; 35(8): 3591-7, 2015 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25716857
15.
Pathogenic mechanisms of prion protein, amyloid-ß and α-synuclein misfolding: the prion concept and neurotoxicity of protein oligomers.
J Neurochem
; 139(2): 162-180, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27529376
16.
Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse.
Neurobiol Dis
; 81: 168-75, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25796563
17.
Metal chaperones prevent zinc-mediated cognitive decline.
Neurobiol Dis
; 81: 196-202, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25549871
18.
Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way.
Neurobiol Dis
; 81: 38-48, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26117305
19.
Comparative Study of Metal Quantification in Neurological Tissue Using Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Imaging and X-ray Fluorescence Microscopy.
Anal Chem
; 87(13): 6639-45, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26020362
20.
Serotonergic markers in Parkinson's disease and levodopa-induced dyskinesias.
Mov Disord
; 30(6): 796-804, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25649148