Detalhe da pesquisa
1.
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions.
Nature
; 559(7713): 285-289, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29973717
2.
Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis.
Genes Dev
; 30(19): 2158-2172, 2016 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27737959
3.
cGAS surveillance of micronuclei links genome instability to innate immunity.
Nature
; 548(7668): 461-465, 2017 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28738408
4.
RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition.
EMBO J
; 37(15)2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29959219
5.
DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency.
Am J Hum Genet
; 103(6): 1038-1044, 2018 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30503519
6.
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
EMBO J
; 35(8): 831-44, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26903602
7.
Corrigendum: Mutations in genes encoding condensins cause microcephaly through decatenation failure at mitosis.
Genes Dev
; 31(9): 953, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28566537
8.
Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions.
Nat Genet
; 51(1): 96-105, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30478443
9.
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism.
Nat Genet
; 48(1): 36-43, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26595769
10.
The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain.
Neurosci Lett
; 609: 11-7, 2015 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26455863