Detalhe da pesquisa
1.
Combining monoamine oxidase B and semicarbazide-sensitive amine oxidase enzyme inhibition to address inflammatory disease.
Bioorg Med Chem Lett
; 74: 128942, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35973549
2.
The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.
J Cell Mol Med
; 23(3): 1759-1770, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30536539
3.
Effects of an anti-inflammatory VAP-1/SSAO inhibitor, PXS-4728A, on pulmonary neutrophil migration.
Respir Res
; 16: 42, 2015 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25889951
4.
PXS-4681A, a potent and selective mechanism-based inhibitor of SSAO/VAP-1 with anti-inflammatory effects in vivo.
J Pharmacol Exp Ther
; 347(2): 365-74, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23943052
5.
The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1).
Bioorg Med Chem Lett
; 22(12): 3935-40, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22595173
6.
Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3.
J Med Chem
; 62(21): 9874-9889, 2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31580073
7.
Synthetic Studies on the Natural Product Myrsinoic Acid F Reveal Biologically Active Analogues.
Org Lett
; 20(13): 3984-3987, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29888922
8.
Inhibition of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 reduces lipopolysaccharide-induced neuroinflammation.
Br J Pharmacol
; 174(14): 2302-2317, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28437839
9.
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.
Oncotarget
; 8(16): 26066-26078, 2017 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199967
10.
An activity-based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti-fibrotic therapeutic strategies.
Clin Transl Med
; 11(11): e572, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34841699
11.
Synthesis of the integrastatin nucleus using the Ramberg-Bäcklund reaction.
Org Lett
; 5(23): 4441-4, 2003 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-14602020
12.
Protein-protein coupling and its application to functional red cell substitutes.
Chem Commun (Camb)
; 46(8): 1194-202, 2010 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20449249
13.
Hemoglobin bis-tetramers via cooperative azide-alkyne coupling.
Chem Commun (Camb)
; (47): 7315-7, 2009 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20024213
14.
Tandem oxidation processes using manganese dioxide: discovery, applications, and current studies.
Acc Chem Res
; 38(11): 851-69, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16285708
15.
Unexpected Z-stereoselectivity in the Ramberg-Bäcklund reaction of diarylsulfones leading to cis-stilbenes: the effect of aryl substituents and application in the synthesis of the integrastatin nucleus.
Org Biomol Chem
; 3(5): 756-63, 2005 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15731861
16.
An empirical study of the effect of the variables in a flash vacuum pyrolysis (FVP) experiment.
Org Biomol Chem
; 2(18): 2677-83, 2004 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15351833