Detalhe da pesquisa
1.
Exploring the structure-activity relationship of benzylidene-2,3-dihydro-1H-inden-1-one compared to benzofuran-3(2H)-one derivatives as inhibitors of tau amyloid fibers.
Eur J Med Chem
; 231: 114139, 2022 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35101652
2.
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity.
Eur J Med Chem
; 190: 112116, 2020 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32078860
3.
Chimeric Protein-Protein Interface Inhibitors Allow Efficient Inhibition of Type III Secretion Machinery and Pseudomonas aeruginosa Virulence.
ACS Infect Dis
; 5(11): 1843-1854, 2019 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31525902
4.
New pseudodimeric aurones as palm pocket inhibitors of Hepatitis C virus RNA-dependent RNA polymerase.
Eur J Med Chem
; 115: 217-29, 2016 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27017550
5.
A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo.
Eur J Med Chem
; 83: 455-65, 2014 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24992073
6.
New 7-methylguanine derivatives targeting the influenza polymerase PB2 cap-binding domain.
J Med Chem
; 56(21): 8915-30, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24134208
7.
Discovery of naturally occurring aurones that are potent allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
J Med Chem
; 54(15): 5395-402, 2011 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21699179
8.
2-Arylidenedihydroindole-3-ones: design, synthesis, and biological activity on bladder carcinoma cell lines.
Bioorg Med Chem Lett
; 17(1): 208-13, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17049235
9.
Toward a better understanding of the basis of the molecular mimicry of polysaccharide antigens by peptides: the example of Shigella flexneri 5a.
J Biol Chem
; 281(4): 2317-32, 2006 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16251186