Detalhe da pesquisa
1.
Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.
Physiol Rev
; 96(1): 253-305, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26676145
2.
Mice lacking α-, ß1- and ß2-syntrophins exhibit diminished function and reduced dystrophin expression in both cardiac and skeletal muscle.
Hum Mol Genet
; 28(3): 386-395, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30256963
3.
Syntrophin binds directly to multiple spectrin-like repeats in dystrophin and mediates binding of nNOS to repeats 16-17.
Hum Mol Genet
; 27(17): 2978-2985, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29790927
4.
Targeted deletion of ß1-syntrophin causes a loss of Kir 4.1 from Müller cell endfeet in mouse retina.
Glia
; 67(6): 1138-1149, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30803043
5.
Altered short-term synaptic plasticity and reduced muscle strength in mice with impaired regulation of presynaptic CaV2.1 Ca2+ channels.
Proc Natl Acad Sci U S A
; 113(4): 1068-73, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26755585
6.
Sarcolemmal targeting of nNOSµ improves contractile function of mdx muscle.
Hum Mol Genet
; 25(1): 158-66, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26604149
7.
A new therapeutic effect of simvastatin revealed by functional improvement in muscular dystrophy.
Proc Natl Acad Sci U S A
; 112(41): 12864-9, 2015 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26417069
8.
Loss of nNOS inhibits compensatory muscle hypertrophy and exacerbates inflammation and eccentric contraction-induced damage in mdx mice.
Hum Mol Genet
; 24(2): 492-505, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25214536
9.
Validation of ultrasonography for non-invasive assessment of diaphragm function in muscular dystrophy.
J Physiol
; 594(24): 7215-7227, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27570057
10.
Lipid abnormalities in alpha/beta2-syntrophin null mice are independent from ABCA1.
Biochim Biophys Acta
; 1851(5): 527-36, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25625330
11.
Evaluation of the specificity of four commercially available antibodies to alpha-syntrophin.
Anal Biochem
; 484: 99-101, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26079703
12.
Regional registration of [6-(14)C]glucose metabolism during brain activation of α-syntrophin knockout mice.
J Neurochem
; 125(2): 247-59, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23346911
13.
Adiponectin receptor 1 C-terminus interacts with PDZ-domain proteins such as syntrophins.
Exp Mol Pathol
; 95(2): 180-6, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23860432
14.
Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy.
J Pathol
; 228(1): 77-87, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22653783
15.
rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.
Nat Med
; 12(7): 787-9, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16819550
16.
Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy.
Proc Natl Acad Sci U S A
; 107(44): 19079-83, 2010 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20956307
17.
Nicotinic acetylcholine receptor stability at the NMJ deficient in α-syntrophin in vivo.
J Neurosci
; 31(43): 15586-96, 2011 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22031904
18.
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier.
Glia
; 60(3): 432-40, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22131281
19.
α-Syntrophin is required for the hepatocyte growth factor-induced migration of cultured myoblasts.
Exp Cell Res
; 317(20): 2914-24, 2011 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22001117
20.
The alpha-syntrophin PH and PDZ domains scaffold acetylcholine receptors, utrophin, and neuronal nitric oxide synthase at the neuromuscular junction.
J Neurosci
; 30(33): 11004-10, 2010 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20720107