Detalhe da pesquisa
1.
HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis.
Cell
; 166(5): 1257-1268.e12, 2016 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27565348
2.
Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential.
Nat Prod Rep
; 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38629495
3.
Discovery and development of botanical natural products and their analogues as therapeutics for ovarian cancer.
Nat Prod Rep
; 40(7): 1250-1270, 2023 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37387219
4.
Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models.
Mol Pharm
; 20(6): 3049-3059, 2023 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155928
5.
Discovery of Anticancer Agents of Diverse Natural Origin.
J Nat Prod
; 85(3): 702-719, 2022 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213158
6.
STarFish: A Stacked Ensemble Target Fishing Approach and its Application to Natural Products.
J Chem Inf Model
; 59(11): 4906-4920, 2019 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31589422
7.
Potential Anticancer Agents Characterized from Selected Tropical Plants.
J Nat Prod
; 82(3): 657-679, 2019 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30830783
8.
Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing.
J Biol Chem
; 292(48): 19814-19825, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972144
9.
Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones.
Bioorg Med Chem
; 26(9): 2354-2364, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29656990
10.
Total Synthesis of Scytonemide A Employing Weinreb AM Solid-Phase Resin.
J Nat Prod
; 81(3): 534-542, 2018 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29400964
11.
Calothrixamides A and B from the Cultured Cyanobacterium Calothrix sp. UIC 10520.
J Nat Prod
; 81(9): 2083-2090, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30192537
12.
A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain.
J Biol Chem
; 291(45): 23569-23577, 2016 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27645997
13.
Pentalinonsterol, a Constituent of Pentalinon andrieuxii, Possesses Potent Immunomodulatory Activity and Primes T Cell Immune Responses.
J Nat Prod
; 80(9): 2515-2523, 2017 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28876059
14.
Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation.
J Virol
; 89(19): 9765-80, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26178982
15.
A new class of multimerization selective inhibitors of HIV-1 integrase.
PLoS Pathog
; 10(5): e1004171, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24874515
16.
Indole-based allosteric inhibitors of HIV-1 integrase.
Bioorg Med Chem Lett
; 26(19): 4748-4752, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27568085
17.
Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation.
Proc Natl Acad Sci U S A
; 110(21): 8690-5, 2013 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23610442
18.
A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase.
J Biol Chem
; 289(38): 26430-26440, 2014 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25118283
19.
TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism.
J Virol
; 88(17): 9704-17, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24942577
20.
Trichormamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater cyanobacterium cf. Oscillatoria sp. UIC 10045.
Bioorg Med Chem
; 23(13): 3153-62, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26001342