Detalhe da pesquisa
1.
Discovery and structure-activity relationship study of 2-piperazinyl-benzothiazole derivatives as potent and selective PPARδ agonists.
Bioorg Med Chem
; 82: 117215, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840990
2.
Discovery and structure-based design of a new series of potent and selective PPARδ agonists utilizing a virtual screening method.
Bioorg Med Chem Lett
; 59: 128567, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35063634
3.
Transdermal administration of aqueous pregabalin solution as a potential treatment option for patients with neuropathic pain to avoid central nervous system-mediated side effects.
Biol Pharm Bull
; 37(11): 1816-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25212662
4.
Design, synthesis and evaluation of retinoids with novel bulky hydrophobic partial structures.
Bioorg Med Chem
; 21(14): 4342-50, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23685180
5.
Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure.
J Med Chem
; 66(16): 11428-11446, 2023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552807
6.
(R)- and (S)-4-Amino-3-(trimethylsilyl)methylbutanoic acids ameliorate neuropathic pain without central nervous system-related side effects.
Bioorg Med Chem Lett
; 22(24): 7602-4, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23103098
7.
Tamibarotene: a candidate retinoid drug for Alzheimer's disease.
Biol Pharm Bull
; 35(8): 1206-12, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863914
8.
Diphenylamine-based retinoid antagonists: regulation of RAR and RXR function depending on the N-substituent.
Bioorg Med Chem
; 19(8): 2501-7, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21459577
9.
Aldosterone-induced kidney injury is mediated by NFκB activation.
Clin Exp Nephrol
; 15(1): 41-9, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21072674
10.
[Retinoid therapy for autoimmune diseases].
Nihon Rinsho Meneki Gakkai Kaishi
; 29(3): 114-26, 2006 Jun.
Artigo
em Japonês
| MEDLINE | ID: mdl-16819260
11.
Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury.
Cardiovasc Res
; 63(1): 51-9, 2004 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15194461
12.
Novel retinoid X receptor antagonists: specific inhibition of retinoid synergism in RXR-RAR heterodimer actions.
J Med Chem
; 45(16): 3327-30, 2002 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12139443
13.
Silicon-containing GABA derivatives, silagaba compounds, as orally effective agents for treating neuropathic pain without central-nervous-system-related side effects.
ACS Chem Neurosci
; 5(7): 525-32, 2014 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24738473
14.
Cooperative therapeutic action of retinoic acid receptor and retinoid x receptor agonists in a mouse model of Alzheimer's disease.
J Alzheimers Dis
; 42(2): 587-605, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24916544
15.
A novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue.
PLoS One
; 8(9): e75445, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24066181
16.
Potent and selective partial ecdysone agonist activity of chromafenozide in Sf9 cells.
Biochem Biophys Res Commun
; 292(4): 1087-91, 2002 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-11944927
17.
Determination of endogenous levels of retinoic acid isomers in type II diabetes mellitus patients. Possible correlation with HbA1c values.
Biol Pharm Bull
; 25(10): 1268-71, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12392076