RESUMO
A screening of coronavirus disease 2019 (COVID-19) polymerase chain reaction (PCR) tests using saliva for pregnant women and their partners was performed at all 12 maternity facilities located in Himeji city between May 29 and September 5, 2020. Pregnant women at 37 or more weeks of gestation or who experienced threatened labor and their partners who cared for an infant underwent a saliva PCR test with informed consent. As a result, all of 1475 pregnant women and 1343 partners tested negative for COVID-19 PCR. There were no cases of false positive or false negative PCR tests. This cohort study revealed for the first time that a screening of COVID-19 PCR tests using saliva may be useful to sustain perinatal medical care during the pandemic period in Japan.
Assuntos
COVID-19/diagnóstico , Complicações Infecciosas na Gravidez/diagnóstico , SARS-CoV-2/isolamento & purificação , Saliva/virologia , Estudos de Coortes , Programas de Triagem Diagnóstica , Reações Falso-Negativas , Reações Falso-Positivas , Feminino , Humanos , Japão , Masculino , Assistência Perinatal , Gravidez , Reação em Cadeia da Polimerase Via Transcriptase Reversa , CônjugesRESUMO
We encountered an elderly married couple with concurrent vulvar and penile carcinoma with an Asian variant of human papillomavirus type 16. Asian variants might have an elevated risk of concurrent external genital carcinomas of a male and a female, and analysis of human papillomavirus variants might be important to understand the mechanism of carcinogenesis.
Assuntos
Carcinoma de Células Escamosas/patologia , Papillomaviridae/isolamento & purificação , Infecções por Papillomavirus/patologia , Neoplasias Penianas/patologia , Cônjuges , Neoplasias Vulvares/patologia , Idoso de 80 Anos ou mais , Carcinoma de Células Escamosas/genética , Carcinoma de Células Escamosas/virologia , DNA Viral/genética , DNA Viral/isolamento & purificação , Feminino , Variação Genética , Papillomavirus Humano 16/genética , Papillomavirus Humano 16/isolamento & purificação , Humanos , Masculino , Infecções por Papillomavirus/genética , Neoplasias Penianas/genética , Neoplasias Penianas/virologia , Reação em Cadeia da Polimerase , Neoplasias Vulvares/genética , Neoplasias Vulvares/virologiaRESUMO
There have been an increasing number of aged patients with malignancies. But, there are some patients who can not receive anti-cancer therapy due to poor activities of daily living and/or aging, etc. In Japan, medical practice at cancer patients' home has been expected for best supportive care, and most physicians believe that home chemotherapy is difficult because cancer patients frequently develop complications. We herein report a case of an 89-year-old female affected by malignant lymphoma who received a home chemotherapy and achieved a good remission. The clinical course of the present case suggested that with careful preparations, home chemotherapy might be feasible and one of therapeutic options for cancer patients.