Detalhe da pesquisa
1.
Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Immunity
; 55(12): 2285-2299.e7, 2022 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36272416
2.
MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress.
Blood
; 139(8): 1184-1197, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33908607
3.
HIF-1α is required for development of the sympathetic nervous system.
Proc Natl Acad Sci U S A
; 116(27): 13414-13423, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31196952
4.
Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype.
J Virol
; 89(17): 9080-9, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26109726
5.
Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice.
Arterioscler Thromb Vasc Biol
; 35(11): 2316-25, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26404487
6.
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.
J Enzyme Inhib Med Chem
; 30(5): 689-721, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25347767
7.
The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II.
J Cell Sci
; 125(Pt 4): 956-64, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22399808
8.
GSK-3ß regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α.
Blood
; 119(5): 1292-301, 2012 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22144179
9.
NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages.
J Biol Chem
; 287(7): 4835-52, 2012 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22157766
10.
Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome.
iScience
; 25(1): 103596, 2022 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34988410
11.
Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease.
Physiol Genomics
; 43(2): 87-98, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20978110
12.
Identification of a survival-independent metastasis-enhancing role of hypoxia-inducible factor-1alpha with a hypoxia-tolerant tumor cell line.
J Biol Chem
; 285(34): 26182-9, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20566631
13.
Phosphodiesterase 2 mediates redox-sensitive endothelial cell proliferation and angiogenesis by thrombin via Rac1 and NADPH oxidase 2.
Circ Res
; 104(10): 1169-77, 2009 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19390057
14.
Compound Mutation in Cardiac Sarcomere Proteins Is Associated with Increased Risk for Major Arrhythmic Events in Pediatric Onset Hypertrophic Cardiomyopathy.
J Clin Med
; 10(22)2021 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830538
15.
Molecular signaling pathways in right ventricular impairment of adult patients after tetralogy of Fallot repair.
Cardiovasc Diagn Ther
; 11(6): 1295-1309, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35070799
16.
Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner.
Mol Cell Biol
; 27(9): 3253-65, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17325032
17.
Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells.
Mol Biol Cell
; 18(12): 4691-7, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17898080
18.
NADPH oxidases and HIF1 promote cardiac dysfunction and pulmonary hypertension in response to glucocorticoid excess.
Redox Biol
; 34: 101536, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32413743
19.
Functional analyses reveal the greater potency of preadipocytes compared with adipocytes as endothelial cell activator under normoxia, hypoxia, and TNFalpha exposure.
Am J Physiol Endocrinol Metab
; 297(3): E735-48, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19549791
20.
The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaison.
Biochem J
; 412(3): e17-9, 2008 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18498249