Detalhe da pesquisa
1.
Human Lung Tissue Implanted on the Chick Chorioallantoic Membrane as a Novel In Vivo Model of Idiopathic Pulmonary Fibrosis.
Am J Respir Cell Mol Biol
; 67(2): 164-172, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35612953
2.
Phase 2 clinical trial of PBI-4050 in patients with idiopathic pulmonary fibrosis.
Eur Respir J
; 53(3)2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30578394
3.
A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.
Am J Pathol
; 188(5): 1132-1148, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29454750
4.
PBI-4050 via GPR40 activation improves adenine-induced kidney injury in mice.
Clin Sci (Lond)
; 133(14): 1587-1602, 2019 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31308217
5.
PBI-4050 Reduces Stellate Cell Activation and Liver Fibrosis through Modulation of Intracellular ATP Levels and the Liver Kinase B1/AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway.
J Pharmacol Exp Ther
; 367(1): 71-81, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30093459
6.
Fourteen-Day Evolution of COVID-19 Symptoms during the Third Wave in Nonvaccinated Subjects and Effects of Hesperidin Therapy: A Randomized, Double-Blinded, Placebo-Controlled Study.
Evid Based Complement Alternat Med
; 2022: 3125662, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36387348
7.
PBI-4050 reduces pulmonary hypertension, lung fibrosis, and right ventricular dysfunction in heart failure.
Cardiovasc Res
; 116(1): 171-182, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753422
8.
Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease.
Sci Rep
; 10(1): 12778, 2020 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728158
9.
Design and Synthesis of New 1,3,5-Trisubstituted Triazines for the Treatment of Cancer and Inflammation.
ChemistryOpen
; 7(9): 737-749, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30258746
10.
Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control.
JCI Insight
; 3(10)2018 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29769449
11.
2,4,6-trisubstituted triazines as protein a mimetics for the treatment of autoimmune diseases.
J Med Chem
; 53(3): 1138-45, 2010 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20047277
12.
Enhancement of Th1 type cytokine production and primary T cell activation by PBI-1393.
Clin Immunol
; 125(3): 318-27, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17827067